苄哒唑
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- CAS号:
- 22994-85-0
- 英文名:
- Benznidazole
- 英文别名:
- ro71051;radanil;Rochagan;Aids007909;NSC 299972;Ro 07-1051;Aids-007909;Benznidazol;benznidazole;Benzonidazol
- 中文名:
- 苄哒唑
- 中文别名:
- 苄哒唑;苄硝唑;苯硝唑;苄哒唑杂质;苯并乙唑-[D7]/精确称量;N-苄基-2-硝基-1H-咪唑-1-乙酰胺;N-苄基-2-(2-硝基-1H-咪唑-1-基)乙酰胺
- CBNumber:
- CB9390906
- 分子式:
- C12H12N4O3
- 分子量:
- 260.25
- MOL File:
- 22994-85-0.mol
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苄哒唑化学性质
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熔点:
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189-192 °C (lit.)
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密度:
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1.35±0.1 g/cm3(Predicted)
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储存条件:
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Sealed in dry,Room Temperature
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溶解度:
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methanol: soluble50mg/mL, clear, colorless to yellow
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酸度系数(pKa):
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14?+-.0.46(Predicted)
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形态:
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Solid
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颜色:
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White to Off-White
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水溶解性:
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0.4g/L(temperature not stated)
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Merck:
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13,1085
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BCS Class:
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3
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苄哒唑性质、用途与生产工艺
苄哒唑可用作医药合成中间体。如果吸入苄哒唑，请将患者移到新鲜空气处；如果皮肤接触，应脱去污染的衣着，用肥皂水和清水彻底冲洗皮肤，如有不适感，就医；如果眼晴接触，应分开眼睑，用流动清水或生理盐水冲洗，并立即就医；如果食入，立即漱口，禁止催吐，应立即就医。
Benznidazole (Radanil)是一种硝基咪唑衍生物，能够干扰寄生虫蛋白质的生物合成、影响其细胞因子的产生、刺激宿主的吞噬作用，因而具有抗原虫活性。
Benznidazole (100 mg/kg/day, p.o., 30 days) produces a decrease in electrocardiographic alterations, fewer modifications in the affinity and density of cardiac-receptors, and few isolated areas of fibrosis in the heart, in mice infected with
Trypanosoma cruzi
Tulahuen strain or SGO-Z12 isolate and treated at 180 days post infection (p.i.) (i.e. chronic phase) with Benznidazole.
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Animal Model:
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Mice infected with
Trypanosoma cruzi
Tulahuen strain or SGO-Z12
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Dosage:
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100 mg/kg/day
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Administration:
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Orally for 30 days
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Result:
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Produced a decrease in electrocardiographic alterations, fewer modifications in the affinity and density of cardiac-receptors, and few isolated areas of fibrosis in the heart.
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苄哒唑
上下游产品信息
上游原料
下游产品
| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
|---|
| 2025/02/08 | HY-B1548 | 苄哒唑
Benznidazol | 22994-85-0 | 25mg | 400元 |
| 2025/02/08 | HY-B1548 | 苄哒唑
Benznidazol | 22994-85-0 | 10mM * 1mLin DMSO | 440元 |
苄哒唑
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22994-85-0, 苄哒唑 相关搜索:
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- Imidazoles
- 苯并乙唑-[D7]/精确称量
- N-苄基-2-(2-硝基-1H-咪唑-1-基)乙酰胺
- 苄哒唑杂质
- 苯硝唑
- N-苄基-2-硝基-1H-咪唑-1-乙酰胺
- 苄哒唑
- 苄硝唑
- 22994-85-0
- N-Benzyl-2-nitro-1H-imidazole-1-acetamide
- Benznidazol,Ro71051,inhibit,Inhibitor,Parasite,Ro-71051
- Benznidazol CAS NO.22994-85-0
- BENZNIDAZOLE (Ro 07-1051)
- Benznidazol (Synonyms: Ro 07-1051
- Benznidazol (Ro 07-1051
- 2-nitro-n-(phenylmethyl)-1h-imidazole-1-acetamide
- 2-nitro-n-(phenylmethyl)-1h-imidazole-1-acetamid
- N-Benzyl-2-nitro-1H-imidazole-1-acetamide 97%
- 1H-IMidazole-1-acetaMide, 2-nitro-N-(phenylMethyl)-
- Rochagan
- Ro 07-1051
- NSC 299972
- N-Benzyl-2-nitroiMidazol-1-yl-acetaMide
- Benznidazol
- Aids-007909
- Aids007909
- N-BENZYL-2-NITRO-1 H-IMIDAZOLE-1-ACETAMIDE
- Benzonidazol
- BenznidazoleBenznidazole
- ro71051
- radanil
- benzonidazole
- benznidazole
- n-benzyl-2-nitroimidazole-1-acetamide
- n-benzyl-2-nitro-imidazole-1-acetamid
- n-benzyl-2-nitro-1-imidazoleacetamide
- n-benzyl-2-(nitroimidazol-1-yl)-acetamid