抗氧化肽A
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- CAS号:
- 159147-88-3
- 英文名:
- H-PRO-HIS-CYS-LYS-ARG-MET-OH
- 英文别名:
- PHCKRM;ANTIOXIDANT PEPTIDE A;H-PRO-HIS-CYS-LYS-ARG-MET-OH;L-Methionine, L-prolyl-L-histidyl-L-cysteinyl-L-lysyl-L-arginyl-;(2S)-2-[[(2S)-2-[[(2S)-6-amino-2-[[(2R)-2-[[(2S)-3-(1H-imidazol-5-yl)-2-[[(2S)-pyrrolidine-2-carbonyl]amino]propanoyl]amino]-3-sulfanylpropanoyl]amino]hexanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-4-methylsulfanylbutanoicacid;H-Pro-His-Cys-Lys-Arg-Met-OH?/(2S)-2-[[(2S)-2-[[(2S)-6-amino-2-[[(2R)-2-[[(2S)-3-(1H-imidazol-5-yl)-2-[[(2S)-pyrrolidine-2-carbonyl]amino]propanoyl]amino]-3-sulfanylpropanoyl]amino]hexanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-4-methylsulfanylbutanoic acid
- 中文名:
- 抗氧化肽A
- 中文别名:
- 抗氧化多肽A;抗氧化肽 A;抗氧化肽A、ANTIOXIDANT PEPTIDE A;(2S)-2-[[(2S)-2-[[(2S)-6-AMINO-2-[[(2R)-2-[[(2S)-3-(1H-IMIDAZOL-5-YL)-2-[[(2S)-PYRROLIDINE-2-CARBONYL]AMINO]PROPANOYL]AMINO]-3-SULFANYLPROPANOYL]AMINO]HEXANOYL]AMINO]-5-(DIAMINOMETHYLIDENEAMINO)PENTANOYL]AMINO]-4-METHYLSULFANYLBUTANOIC ACID
- CBNumber:
- CB9398902
- 分子式:
- C31H54N12O7S2
- 分子量:
- 770.97
- MOL File:
- Mol file
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抗氧化肽A化学性质
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密度:
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1.51±0.1 g/cm3(Predicted)
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储存条件:
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-15°C
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酸度系数(pKa):
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3.22±0.10(Predicted)
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序列:
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H-Pro-His-Cys-Lys-Arg-Met-OH
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抗氧化肽A性质、用途与生产工艺
Antioxidant peptide A 是一种短肽。作用于癌细胞时，Antioxidant peptide A 的侧链有助于增强自由基清除活性。
The effects of 10-100 μM of Antioxidant peptide A (Pep-A) concentrations are studied on the superoxide dismutase (SOD) enzyme activity. The enzyme activity decreases by 0.5 and 0.7-folds at 10 and 50 µM Antioxidant peptide A concentrations, respectively, and increases by 1.79-folds at 100 µM Antioxidant peptide A treatment, indicating that this concentration can be ideal for the treatment on Y79 a, RB cells. Furthermore, the Antioxidant peptide A can be involved in decreasing the ROS by increasing the antioxidant enzyme activity. A similar increase in the antioxidative enzyme levels in the presence of Hoki skin antioxidative peptide in hepatocarcinoma cells is attributed to the peptide’s role in maintaining the redox balance in the cellular environment. Cell viability analysis results show that the Antioxidant peptide A shows no toxicity to cancerous (Y79) cells and non-cancerous cells even after 48 h of treatment. The Y79 RB cell viability ranges between 115 and 157 % and 111-126 % after 24 and 48 h of exposures with Antioxidant peptide A, respectively. The cancer cell death from the treatment of 10-100 µM GNPs concentration is studied.
多肽
抗氧化肽A 是一条很有巯基的短肽，是由6个氨基酸组成。在生物体内，它作用于癌细胞时，序列中的侧链有助于增强自由基清除活性。此外，抗氧化肽A可通过提高抗氧化酶活性参与降低氧自由基，并且作为抗氧化肽进入生物体内后，不会存在毒副作用。
参考质量标准
外观:白色粉末
纯度(HPLC) ≥98.0%
醋酸根含量≤12.0%
水分含量≤8.0%
肽含量≥80.0%
内毒素≤50EU/mg
氨基酸组成分析≤±10%
抗氧化肽A
上下游产品信息
上游原料
下游产品
| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
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| 2023/03/20 | HY-P1512 | H-PRO-HIS-CYS-LYS-ARG-MET-OH
Antioxidant peptide A | 159147-88-3 | 1mg | 900元 |
| 2023/03/20 | HY-P1512 | H-PRO-HIS-CYS-LYS-ARG-MET-OH
Antioxidant peptide A | 159147-88-3 | 5mg | 2700元 |
159147-88-3, 抗氧化肽A 相关搜索:
- peptide
- 目录肽
- 优势产品
- 目录多肽
- 多肽
- 抗氧化肽A、ANTIOXIDANT PEPTIDE A
- 抗氧化多肽A
- (2S)-2-[[(2S)-2-[[(2S)-6-AMINO-2-[[(2R)-2-[[(2S)-3-(1H-IMIDAZOL-5-YL)-2-[[(2S)-PYRROLIDINE-2-CARBONYL]AMINO]PROPANOYL]AMINO]-3-SULFANYLPROPANOYL]AMINO]HEXANOYL]AMINO]-5-(DIAMINOMETHYLIDENEAMINO)PENTANOYL]AMINO]-4-METHYLSULFANYLBUTANOIC ACID
- 抗氧化肽 A
- 159147-88-3
- L-Methionine, L-prolyl-L-histidyl-L-cysteinyl-L-lysyl-L-arginyl-
- (2S)-2-[[(2S)-2-[[(2S)-6-amino-2-[[(2R)-2-[[(2S)-3-(1H-imidazol-5-yl)-2-[[(2S)-pyrrolidine-2-carbonyl]amino]propanoyl]amino]-3-sulfanylpropanoyl]amino]hexanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-4-methylsulfanylbutanoicacid
- H-Pro-His-Cys-Lys-Arg-Met-OH?/(2S)-2-[[(2S)-2-[[(2S)-6-amino-2-[[(2R)-2-[[(2S)-3-(1H-imidazol-5-yl)-2-[[(2S)-pyrrolidine-2-carbonyl]amino]propanoyl]amino]-3-sulfanylpropanoyl]amino]hexanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-4-methylsulfanylbutanoic acid
- ANTIOXIDANT PEPTIDE A
- H-PRO-HIS-CYS-LYS-ARG-MET-OH
- PHCKRM