抗氧化肽A
中文名称 | 抗氧化肽A |
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中文同义词 | 抗氧化肽 A;(2S)-2-[[(2S)-2-[[(2S)-6-AMINO-2-[[(2R)-2-[[(2S)-3-(1H-IMIDAZOL-5-YL)-2-[[(2S)-PYRROLIDINE-2-CARBONYL]AMINO]PROPANOYL]AMINO]-3-SULFANYLPROPANOYL]AMINO]HEXANOYL]AMINO]-5-(DIAMINOMETHYLIDENEAMINO)PENTANOYL]AMINO]-4-METHYLSULFANYLBUTANOIC ACID;抗氧化多肽A;抗氧化肽A、ANTIOXIDANT PEPTIDE A |
英文名称 | H-PRO-HIS-CYS-LYS-ARG-MET-OH |
英文同义词 | PHCKRM;H-PRO-HIS-CYS-LYS-ARG-MET-OH;ANTIOXIDANT PEPTIDE A;H-Pro-His-Cys-Lys-Arg-Met-OH?/(2S)-2-[[(2S)-2-[[(2S)-6-amino-2-[[(2R)-2-[[(2S)-3-(1H-imidazol-5-yl)-2-[[(2S)-pyrrolidine-2-carbonyl]amino]propanoyl]amino]-3-sulfanylpropanoyl]amino]hexanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-4-methylsulfanylbutanoic acid;(2S)-2-[[(2S)-2-[[(2S)-6-amino-2-[[(2R)-2-[[(2S)-3-(1H-imidazol-5-yl)-2-[[(2S)-pyrrolidine-2-carbonyl]amino]propanoyl]amino]-3-sulfanylpropanoyl]amino]hexanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-4-methylsulfanylbutanoicacid;L-Methionine, L-prolyl-L-histidyl-L-cysteinyl-L-lysyl-L-arginyl- |
CAS号 | 159147-88-3 |
分子式 | C31H54N12O7S2 |
分子量 | 770.97 |
EINECS号 | |
相关类别 | 多肽;目录多肽;peptide |
Mol文件 | Mol File |
结构式 | ![]() |
抗氧化肽A 性质
密度 | 1.51±0.1 g/cm3(Predicted) |
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储存条件 | -15°C |
酸度系数(pKa) | 3.22±0.10(Predicted) |
序列 | H-Pro-His-Cys-Lys-Arg-Met-OH |
The effects of 10-100 μM of Antioxidant peptide A (Pep-A) concentrations are studied on the superoxide dismutase (SOD) enzyme activity. The enzyme activity decreases by 0.5 and 0.7-folds at 10 and 50 µM Antioxidant peptide A concentrations, respectively, and increases by 1.79-folds at 100 µM Antioxidant peptide A treatment, indicating that this concentration can be ideal for the treatment on Y79 a, RB cells. Furthermore, the Antioxidant peptide A can be involved in decreasing the ROS by increasing the antioxidant enzyme activity. A similar increase in the antioxidative enzyme levels in the presence of Hoki skin antioxidative peptide in hepatocarcinoma cells is attributed to the peptide’s role in maintaining the redox balance in the cellular environment. Cell viability analysis results show that the Antioxidant peptide A shows no toxicity to cancerous (Y79) cells and non-cancerous cells even after 48 h of treatment. The Y79 RB cell viability ranges between 115 and 157 % and 111-126 % after 24 and 48 h of exposures with Antioxidant peptide A, respectively. The cancer cell death from the treatment of 10-100 µM GNPs concentration is studied.
纯度(HPLC) ≥98.0%
醋酸根含量≤12.0%
水分含量≤8.0%
肽含量≥80.0%
内毒素≤50EU/mg
氨基酸组成分析≤±10%
安全信息
更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
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2023/03/20 | HY-P1512 | H-PRO-HIS-CYS-LYS-ARG-MET-OH Antioxidant peptide A | 159147-88-3 | 1mg | 900元 |
2023/03/20 | HY-P1512 | H-PRO-HIS-CYS-LYS-ARG-MET-OH Antioxidant peptide A | 159147-88-3 | 5mg | 2700元 |