130849-58-0
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- CAS号:
- 130849-58-0
- 英文名:
- Z-321
- 英文别名:
- Z-321;Z321,Z 321;Thiazolidine, 3-[(2,3-dihydro-1H-inden-2-yl)acetyl]-4-(1-pyrrolidinylcarbonyl)-, (4R)- (9CI)
- 中文名:
- 130849-58-0
- 中文别名:
- 化合物 T17279
- CBNumber:
- CB94796702
- 分子式:
- C19H24N2O2S
- 分子量:
- 344.47
- MOL File:
- 130849-58-0.mol
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130849-58-0化学性质
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沸点:
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588.8±50.0 °C(Predicted)
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密度:
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1.265±0.06 g/cm3(Predicted)
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储存条件:
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Store at -20°C
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溶解度:
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DMSO: 250 mg/mL (725.75 mM)
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形态:
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Solid
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酸度系数(pKa):
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-0.84±0.20(Predicted)
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颜色:
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White to off-white
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130849-58-0性质、用途与生产工艺
Z-321 是一个脯氨酰内肽酶 (PEP) 抑制剂。
Z-321 is a prolylendopeptidase (PEP) inhibitor. In the 100 or 200 mg/kg Z-321-treated groups, mean lordosis quotient (LQ) decreases after administration. However, there is no statistical difference among the values before and after. In contrast, the mean LQ in the 300 mg/kg Z-321-treated females is lower than that before injection (P<0.005). Furthermore, when compare to that in the vehicle-treated control group, mean LQ is also significantly lower (p<0.05). The incidence of soliciting behavior decreases after treatment with 300 mg/kg Z-321, when compare to that before treatment, but there is no statistical difference. The present study also demonstrates that 300 mg/kg Z-321 is effective in inhibiting lordosis behavior without disturbance of locomotor activity.
130849-58-0
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更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
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2024/04/30 | HY-19123 | 130849-58-0 Z-321 | 130849-58-0 | 1mg | 2600元 |
2024/04/30 | HY-19123 | 130849-58-0 Z-321 | 130849-58-0 | 5mg | 6000元 |
130849-58-0, 130849-58-0 相关搜索:
- 化合物 T17279
- 130849-58-0
- Z321,Z 321
- Thiazolidine, 3-[(2,3-dihydro-1H-inden-2-yl)acetyl]-4-(1-pyrrolidinylcarbonyl)-, (4R)- (9CI)
- Z-321