130849-58-0
| 中文名称 | 130849-58-0 |
|---|---|
| 中文同义词 | 化合物 T17279 |
| 英文名称 | Z-321 |
| 英文同义词 | Z-321;Thiazolidine, 3-[(2,3-dihydro-1H-inden-2-yl)acetyl]-4-(1-pyrrolidinylcarbonyl)-, (4R)- (9CI);Z321,Z 321 |
| CAS号 | 130849-58-0 |
| 分子式 | C19H24N2O2S |
| 分子量 | 344.47 |
| EINECS号 | |
| 相关类别 | |
| Mol文件 | 130849-58-0.mol |
| 结构式 |  |
130849-58-0 性质
| 沸点 | 588.8±50.0 °C(Predicted) |
|---|---|
| 密度 | 1.265±0.06 g/cm3(Predicted) |
| 储存条件 | Store at -20°C |
| 溶解度 | 二甲基亚砜：250 mg/ml（725.75 mM） |
| 形态 | 固体 |
| 酸度系数(pKa) | -0.84±0.20(Predicted) |
| 颜色 | 白色至米白色 |
PEP
Z-321 is a prolylendopeptidase (PEP) inhibitor. In the 100 or 200 mg/kg Z-321-treated groups, mean lordosis quotient (LQ) decreases after administration. However, there is no statistical difference among the values before and after. In contrast, the mean LQ in the 300 mg/kg Z-321-treated females is lower than that before injection (P<0.005). Furthermore, when compare to that in the vehicle-treated control group, mean LQ is also significantly lower (p<0.05). The incidence of soliciting behavior decreases after treatment with 300 mg/kg Z-321, when compare to that before treatment, but there is no statistical difference. The present study also demonstrates that 300 mg/kg Z-321 is effective in inhibiting lordosis behavior without disturbance of locomotor activity.
安全信息
| 更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
|---|---|---|---|---|---|
| 2024/04/30 | HY-19123 | 130849-58-0 Z-321 | 130849-58-0 | 1mg | 2600元 |
| 2024/04/30 | HY-19123 | 130849-58-0 Z-321 | 130849-58-0 | 5mg | 6000元 |