藏红花醛
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- CAS号:
- 116-26-7
- 英文名:
- SAFRANAL
- 英文别名:
- 1,3-Cyclohexadiene-1-carboxaldehyde, 2,6,6-trimethyl-;2,6,6-Trimethyl-1,3-cyclohexadiene-1-carboxaldehyde;2,6,6-trimethylcyclohexa-1,3-diene-1-carbaldehyde;FEMA 3389;2,3-Dihydro-2,2,6-trimethylbenzalhyde;2,3-DIHYDRO-2,2,6-TRIMETHYLBENZALDEHYDE;SAFRANAL;SAFRANAL 88+%;Safranal (>80%);SAFRANAL USP/EP/BP
- 中文名:
- 藏红花醛
- 中文别名:
- 藏花醛;波斯菊;臧红花醛;藏红花醛;番紅花醛;藏花醛/藏红花醛;SAFRANAL (>80%);藏红花醛,10 MM DMSO 溶液;2,3-二氢-2,2,6-三甲基苯甲醛;2,6,6-三甲基环己-1,3-二烯基甲醛
- CBNumber:
- CB9701548
- 分子式:
- C10H14O
- 分子量:
- 150.22
- MOL File:
- 116-26-7.mol
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藏红花醛化学性质
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熔点:
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<25 °C
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沸点:
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70 °C1 mm Hg(lit.)
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密度:
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0.966 g/mL at 25 °C(lit.)
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蒸气压:
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10.3Pa at 20℃
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折射率:
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n20/D 1.523(lit.)
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FEMA:
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3389 | 2,6,6-TRIMETHYLCYCLOHEXA-1,3-DIENYL METHANAL
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闪点:
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186 °F
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储存条件:
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Inert atmosphere,Store in freezer, under -20°C
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溶解度:
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Chloroform, Ethyl Acetate (Slightly), Methanol (Slightly)
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形态:
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Oil
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颜色:
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Yellow to Dark Yellow
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气味 (Odor):
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at 1.00 % in dipropylene glycol. fresh herbal phenolic metallic rosemary tobacco spicy
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香型:
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herbal
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生物来源:
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synthetic
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水溶解性:
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514.9mg/L at 20℃
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Merck:
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13,8394
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JECFA Number:
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977
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BRN:
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1932918
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稳定性:
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Light Sensitive
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LogP:
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2.7 at 20℃
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EPA化学物质信息:
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1,3-Cyclohexadiene-1-carboxaldehyde, 2,6,6-trimethyl- (116-26-7)
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藏红花醛性质、用途与生产工艺
藏红花醛呈黄色液体状，溶于乙醇等有机溶剂。
藏红花醛是藏红花中含有的一种化学成分，是一种批准为允许使用的食品香料，可用于调配老姆酒、无花果、茶叶以及木香香型、药草香型的食用香精。
藏红花醛可由藏红花中的苦味素一苦藏花素在酸中水解取得，或由β-环柠檬醛或a-环香叶酸用氧化硒催化脱氢制得。
Safranal 是藏红花 (Crocus sativus) 的主要成分，具有口服活性，是这种香料的独特香气来源。Safranal 具有神经保护和抗炎作用，并有用于帕金森氏病的研究潜力。
Safranal (10-50 μM; for 1 h) dose-dependently decreases LPS-induced iNOS and COX-2 levels in both RAW264.7 cells and BMDMs.
Safranal (10-50 μM; for 1 h) inhibits cytokine IL-6 and TNF-α production and mRNA expression in lipopolysaccharide (LPS)-stimulated RAW 264.7 cells.
Safranal (10, 50 μM; for 1 h followed by stimulation with 1 μg/ml of LPS for 30 min) inhibits the nuclear translocation of NF-κB and AP-1 in lipopolysaccharide (LPS)-stimulated RAW264.7 cells.
Western Blot Analysis
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Cell Line:
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RAW264.7 cells and bone marrow-derived macrophages (BMDMs)
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Concentration:
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10, 50 μM
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Incubation Time:
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For 1 h prior to lipopolysaccharide (LPS) stimulation (1 µg/ml)
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Result:
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Dose-dependently decreased LPS-induced iNOS and COX-2 levels in both RAW264.7 cells and BMDMs.
Inhibited the phosphorylation of MAPK pathway proteins extracellular signal-regulated kinase (ERK), c-Jun N-terminal kinase (JNK), p38.
Inhibited NF-κB pathway proteins IKKα/β and IκBα and the degradation of IκBα.
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RT-PCR
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Cell Line:
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RAW 264.7 cells
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Concentration:
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10, 50 μM
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Incubation Time:
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For 1 h followed by stimulation with LPS (1 μg/ml) for 24 h
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Result:
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Inhibited cytokine IL-6 and TNF-α production and mRNA expression in lipopolysaccharide (LPS)-stimulated RAW 264.7 cells.
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Safranal (200-500 mg/kg; PO; for 7 days) causes a slight restoration of colon length and percentage of weight loss, and the DAI score is significantly low.
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Animal Model:
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Female BALB/c mice (18-20 g) (DSS-induced colitis mice)
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Dosage:
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200, 500 mg/kg
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Administration:
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PO; for 7 days
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Result:
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Caused a slight restoration of colon length and percentage of weight loss, and the DAI score is significantly low.
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藏红花醛
上下游产品信息
上游原料
下游产品
| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
|---|
| 2024/11/08 | HY-N7560 | 藏红花醛
Safranal | 116-26-7 | 500mg | 500元 |
藏红花醛
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藏红花醛国内生产厂家
116-26-7, 藏红花醛 相关搜索:
- 医用原料
- 抑制剂
- 其它原料及中间体
- 高端化学
- 醛类
- 有机类
- 有机化工原料
- 精细化工品
- 植物提取物
- 单体香料
- 香精香料
- 化工材料
- 藏红花醛,10 MM DMSO 溶液
- 臧红花醛
- 2,6,6-三甲基环己-1,3-二烯基甲醛(藏红花醛)
- 2,6,6-三甲基环己-1,3-二烯基甲醛
- 波斯菊
- SAFRANAL (>80%)
- 2,3-二氢-2,2,6-三甲基苯甲醛(藏花醛,藏红花醛)
- 藏花醛
- 藏红花醛
- 2,3-二氢-2,2,6-三甲基苯甲醛
- 藏花醛/藏红花醛
- 番紅花醛
- 116-26-7
- Safranal, 10 mM in DMSO
- 1,3-Cyclohexadiene-1-carboxaldehyde, 2,6,6-trimethyl-
- 2,6,6-Trimethyl-1,3-cyclohexadiene-1-carboxaldehyde
- FEMA 3389
- 2,3-DIHYDRO-2,2,6-TRIMETHYLBENZALDEHYDE
- 2,3-Dihydro-2,2,6-trimethylbenzalhyde
- 2,6,6-trimethylcyclohexa-1,3-diene-1-carbaldehyde
- 2,6,6-trimethyl-1-cyclohexa-1,3-dienecarboxaldehyde
- SAFRANAL USP/EP/BP
- safranal,2,6,6-trimethyl-1,3-cyclohexadiene-1-carboxaldehyde
- SAFRANAL TECHN. ABOUT 95%
- SAFRANAL 88+%
- (2,6,6-TRIMETHYLCYCLOHEXA-1,3-DIENYL)METHANAL
- SAFRANAL
- 3-Cyclohexadiene-1-carboxaldehyde,2,6,6-trimethyl-1
- 2,6,6-trimethyl-3-cyclohexadiene-1-carboxaldehyde
- 2,6,6-Trimethyl-1,3-cyclohexadiene-1-carbaldehyde
- 2,6,6-Trimethyl-1,3-cyclohexadienal
- Safranal (>80%)
- 2,6,6-triMethylcyclohexa-1,3-dienecarbaldehyde
- Safranal,2,3-Dihydro-2,2,6-trimethylbenzaldehyde
- 1,1,3-TRIMETHYL-2-FORMYLCYCLOHEXA-2,4-DIENE