苄噻嗪
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- CAS号:
- 91-33-8
- 英文名:
- BENZTHIAZIDE
- 英文别名:
- Exna;exva;p1393;Urese;P 1393;Fovane;fouane;Exsalt;Diucen;Edemex
- 中文名:
- 苄噻嗪
- 中文别名:
- 苄噻嗪;苄硫噻嗪;苯并噻嗪;苄噻嗪杂质;苄硫醚氯噻嗪;苄噻嗪 标准品;苄噻嗪BENZTHIAZIDE
- CBNumber:
- CB9758542
- 分子式:
- C15H14ClN3O4S3
- 分子量:
- 431.94
- MOL File:
- 91-33-8.mol
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苄噻嗪性质、用途与生产工艺
Benzthiazide 是一种长效的利尿剂和抗高血压剂。Benzthiazide 为碳酸酐酶 9 (carbonic anhydrase 9 (CA9)) 的抑制剂，对 CA9，CA2 和 CA1 的 Ki 值分别为 8.0，8.8 和 10 nM。Benzthiazide 能够抑制肿瘤细胞增殖。
Ki: 8.0 nM (CA9), 8.8 nM (CA2), 10 nM (CA1)
Benzthiazide (0.4, 2, 10 μM) suppresses proliferation of cancer cell under hypoxic conditions in a dose-dependent manner
.
Benzthiazide is an inhibitor of carbonic anhydrase 9 (CA9), with K
i
s of 8.0, 8.8 and 10 nM for CA9, CA2 and CA1, respectively.
Benzthiazide (1, 1.5 mg/100 g BW) causes a marked decrease in urinary calcium excretion and the dissociation of calcium and sodium excretion in hyperprolactinemic rats.
类别
有毒物品
毒性分级
高毒
急性毒性
静脉-大鼠 LD50:422 毫克/公斤; 静脉-小鼠 LD50; 410 毫克/公斤
可燃性危险特性
通风低温干燥; 与库房食可燃; 燃烧产生有毒氮氧化物, 硫氧化物和氯化物烟雾
储运特性
通风低温干燥; 与库房食品原料分开存放
灭火剂
干粉,泡沫,沙土,二氧化碳, 雾状水
苄噻嗪
上下游产品信息
上游原料
下游产品
| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
|---|
| 2024/04/30 | HY-B1424 | 苄噻嗪
Benzthiazide | 91-33-8 | 500mg | 350元 |
| 2024/04/30 | HY-B1424 | 苄噻嗪
Benzthiazide | 91-33-8 | 10mM * 1mLin DMSO | 385元 |
苄噻嗪
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91-33-8, 苄噻嗪 相关搜索:
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- S-Containing
- Heterocyclic Building Blocks
- 43194
- C15H14ClN3O4S3
- 苄噻嗪BENZTHIAZIDE
- 苄噻嗪 标准品
- 苯并噻嗪
- 苄噻嗪杂质
- 苄噻嗪
- 苄硫噻嗪
- 苄硫醚氯噻嗪
- 91-33-8
- Hydrochlorothiazide Impurity 31 (Benzthiazide)
- Inhibitor,Carbonate dehydratase,Carbonic Anhydrase,Benzthiazide,inhibit
- 3-((Benzylthio)methyl)-6-chloro-2H-benzo[e][1,2,4]thiadiazine-7-sulfonamide 1,1-dioxide
- BENZTHIAZIDE USP/EP/BP
- Edemex
- diucene
- Diucen
- Dihydrex
- Benzothiazide
- Aquatag
- 6-chloro-7-sulfamoyl-3-benzylthiomethyl-2h-1,2,4-benzothiadiazine1,1-dioxide
- 6-chloro-3-[[(phenylmethyl)thio]methyl]-2h-1,2,4-benzothiadiazine-7-sulfonamid
- 6-chloro-3-(((phenylmethyl)thio)methyl)-2h-1,2,4-benzothiadiazine-7-sulfonamide
- 4or6-chloro-2-phenylphenol
- 4-benzothiadiazine-7-sulfonamide,3-((benzylthio)methyl)-6-chloro-,1,1-2h-2
- 3-benzylthiomethyl-6-chloro-7-sulfamoyl-1,2,4-benzothiadiazine1,1-dioxide
- 3-Benzylthiomethyl-6-chloro-7-sulfamoyl-1,2,4-benzothiadiazine 1,1-dioxide
- 3-benzylthiomethyl-6-chloro-2h-1,2,4-benzothiadiazine-7-sulfonamide1,1-dioxi
- 3-Benzylthiomethyl-6-chloro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide
- 3-[(benzylthio)methyl]-6-chloro-7-sulfamoyl-2h-benzo-1,2,4-thiadiazine1,1-diox
- 3-[(benzylthio)methyl]-6-chloro-2h-1,2,4-benzothiadiazine-7-sulfonamide1,1-dio
- 3-[(Benzylsulfanyl)methyl]-6-chloro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide
- 3-((benzylthio)methyl)-6-chloro-2h-1,2,4-benzothiadiazine-7-sulfonamide1,1-dio
- 3-((Benzylthio)methyl)-6-chloro-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide
- 2h-1,2,4-benzothiadiazine-7-sulfonamide,6-chloro-3-(((phenylmethyl)thio)methyl
- 2h-1,2,4-benzothiadiazine-7-sulfonamide,3-((benzylthio)menthyl)-6-chloro-,1,1
- 2H-1,2,4-Benzothiadiazine-7-sulfonamide, 6-chloro-3-[[(phenylmethyl)thio]methyl]-, 1,1-dioxide
- 2H-1,2,4-Benzothiadiazine-7-sulfonamide, 6-chloro-3-(((phenylmethyl)thio)methyl)-, dioxide
- 2H-1,2,4-Benzothiadiazine-7-sulfonamide, 3-((benzylthio)methyl)-6-chloro-, 1,1-dioxide