[(6,7-dichloro-2,3-dihydro-2-methyl-1-oxo-2-phenyl-1H-inden-5-yl)oxy]acetic acid

生物活性体内研究

CAS号:: 56049-88-8

英文名:: [(6,7-dichloro-2,3-dihydro-2-methyl-1-oxo-2-phenyl-1H-inden-5-yl)oxy]acetic acid

英文别名:: Einecs 259-965-3;[[6,7-Dichloro-2-methyl-2-phenyl-1-oxoindan-5-yl]oxy]acetic acid;[(6,7-dichloro-2,3-dihydro-2-methyl-1-oxo-2-phenyl-1H-inden-5-yl)oxy]acetic acid;Acetic acid, 2-[(6,7-dichloro-2,3-dihydro-2-methyl-1-oxo-2-phenyl-1H-inden-5-yl)oxy]-

中文名:: [(6,7-dichloro-2,3-dihydro-2-methyl-1-oxo-2-phenyl-1H-inden-5-yl)oxy]acetic acid

中文别名:: 化合物 T19430

CBNumber:: CB9932986

分子式:: C18H14Cl2O4

分子量:: 365.21

MOL File:: 56049-88-8.mol

化学性质安全信息用途供应商 5

[(6,7-dichloro-2,3-dihydro-2-methyl-1-oxo-2-phenyl-1H-inden-5-yl)oxy]acetic acid化学性质

熔点:: 167-168 °C(Solv: acetic acid (64-19-7))

沸点:: 553.6±50.0 °C(Predicted)

密度:: 1.422±0.06 g/cm3(Predicted)

储存条件:: Store at -20°C

溶解度:: Soluble in DMSO

酸度系数(pKa):: 2.80±0.10(Predicted)

安全信息

[(6,7-dichloro-2,3-dihydro-2-methyl-1-oxo-2-phenyl-1H-inden-5-yl)oxy]acetic acid性质、用途与生产工艺

生物活性

Indacrinone (MK196) 是一种研究性利尿剂，其在大鼠和狗中具有显着的盐水活性，并且在黑猩猩中具有尿酸和盐水活性。

As the dose increasing from 1 to 10 mg/kg, the amount excreted via the urine decreased from 20 to 11% of administered dose. The amount excretes via the feces is 2-fold higher at the lower dose. At the 10 mg/kg dose the Indacrinone (MK-196)/1 ratio is 0.8 and 5 for the urine and feces, respectively. The urinary ratio of Indacrinone/1 decrease as dose increasing from 10 mg/kg (0.5) to 20 mg/kg (0.2).

[(6,7-dichloro-2,3-dihydro-2-methyl-1-oxo-2-phenyl-1H-inden-5-yl)oxy]acetic acid 上下游产品信息

上游原料

下游产品

[(6,7-dichloro-2,3-dihydro-2-methyl-1-oxo-2-phenyl-1H-inden-5-yl)oxy]acetic acid 生产厂家

全球有 5家供应商 [(6,7-dichloro-2,3-dihydro-2-methyl-1-oxo-2-phenyl-1H-inden-5-yl)oxy]acetic acid国内生产厂家

供应商	联系电话	电子邮件	国家	产品数	优势度
MedChemexpress LLC	021-58955995	sales@medchemexpress.cn	美国	4863	58
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	美国	19892	58
天津普西唐生物医药科技有限公司	010-60605840 15801484223	psaitong@jm-bio.com	中国	29778	58
TargetMol中国（陶术生物）	4008200310	marketing@tsbiochem.com	中国	24647	58

56049-88-8, [(6,7-dichloro-2,3-dihydro-2-methyl-1-oxo-2-phenyl-1H-inden-5-yl)oxy]acetic acid 相关搜索:

抑制剂
化合物 T19430
56049-88-8
Acetic acid, 2-[(6,7-dichloro-2,3-dihydro-2-methyl-1-oxo-2-phenyl-1H-inden-5-yl)oxy]-
Einecs 259-965-3
[[6,7-Dichloro-2-methyl-2-phenyl-1-oxoindan-5-yl]oxy]acetic acid
[(6,7-dichloro-2,3-dihydro-2-methyl-1-oxo-2-phenyl-1H-inden-5-yl)oxy]acetic acid