kijanimicin

kijanimicin Struktur
78798-08-0
CAS-Nr.
78798-08-0
Englisch Name:
kijanimicin
Synonyma:
Sch 25663;kijanimicin;Kijanimicin sodium salt;18H-16a,19-Metheno-16aH-benzo[b]naphth[2,1-j]oxacyclotetradecin-18,20(1H)-dione, 4-[(O-2,6-dideoxy-α-L-ribo-hexopyranosyl-(1→3)-O-[2,6-dideoxy-4-O-methyl-β-L-ribo-hexopyranosyl-(1→4)]-O-2,6-dideoxy-α-L-ribo-hexopyranosyl-(1→3)-2,6-dideoxy-α-L-ribo-hexopyranosyl)oxy]-2,3,4,4a,6a,9,10,12a,15,16,20a,20...
CBNumber:
CB01370573
Summenformel:
C67H100N2O24
Molgewicht:
1317.52
MOL-Datei:
78798-08-0.mol

kijanimicin Eigenschaften

Dichte
1.35±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
Löslichkeit
DMF: soluble; DMSO: soluble; Ethanol: soluble; Methanol: soluble
Aggregatzustand
A solid
pka
4.50±1.00(Predicted)

Sicherheit

kijanimicin Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Kijanimicin is a tetronic acid related to saccharocarcin, chlorothricin, versipelostatin and tetrocarcin. Like the tetrocarcins, kijanimicin contains an unusual nitroaminoglycoside. Kijanimicin is a potent antibacterial, antimalarial and antitumour active. Several members of this class have received considerable literature focus. Versipelostatin inhibits transcription from the promoter of GRP78, a gene that is activated as part of a stress signalling pathway under glucose deprivation resulting in unfolded protein response (UPR). The UPR-inhibitory action is seen only in conditions of glucose deprivation and causes selective and massive killing of the glucose-deprived cells. Tetrocarcin A appears to target the phosphatidylinositide-3'-kinase/Akt signalling pathway.

kijanimicin Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


kijanimicin Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 30)Lieferanten
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TargetMol Chemicals Inc.
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Shanghai Hongye Biotechnology Co. Ltd 400-9205774
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Shenzhen Polymeri Biochemical Technology Co., Ltd. +86-400-002-6226
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ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767
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Meng Cheng Technology (Shanghai) Co., LTD 400-820-6829
sales@mitachieve.com China 8864 58

78798-08-0()Verwandte Suche:


  • kijanimicin
  • Sch 25663
  • 18H-16a,19-Metheno-16aH-benzo[b]naphth[2,1-j]oxacyclotetradecin-18,20(1H)-dione, 4-[(O-2,6-dideoxy-α-L-ribo-hexopyranosyl-(1→3)-O-[2,6-dideoxy-4-O-methyl-β-L-ribo-hexopyranosyl-(1→4)]-O-2,6-dideoxy-α-L-ribo-hexopyranosyl-(1→3)-2,6-dideoxy-α-L-ribo-hexopyranosyl)oxy]-2,3,4,4a,6a,9,10,12a,15,16,20a,20...
  • Kijanimicin sodium salt
  • 78798-08-0
  • C67H100N2O24
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