Calcium levofolinate
|
|
|
- CAS-Nr.
- 80433-71-2
- Englisch Name:
- Calcium levofolinate
- Synonyma:
- levofolinate;levoleucovorin calcium;Calcium Levofolinate Pentahydrate;Isovorin;Elvorine;CL 307782;Calcium leovate;Levofolinatecalcium;l-Form calcium salt;L-LEUCOVORIN CALCIUM
- CBNumber:
- CB0193805
- Summenformel:
- C20H25CaN7O7
- Molgewicht:
- 515.54
- MOL-Datei:
- 80433-71-2.mol
|
Calcium levofolinate Eigenschaften
- Schmelzpunkt:
- 240-2500C (dec)
- alpha
- D20 -15.1° (c = 1.82)
- storage temp.
- Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
- Löslichkeit
- Slightly soluble in water, practically insoluble in acetone and in ethanol (96 per cent).
- Aggregatzustand
- Solid
- Farbe
- Off-White to Pale Beige
- Stabilität:
- Hygroscopic, Light Sensitive
- CAS Datenbank
- 80433-71-2(CAS DataBase Reference)
Sicherheit
- Risiko- und Sicherheitserklärung
- Gefahreninformationscode (GHS)
| Bildanzeige (GHS) |
|
| Alarmwort |
Warnung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H302 |
Gesundheitsschädlich bei Verschlucken. |
Akute Toxizität oral |
Kategorie 4 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P270, P301+P312, P330, P501 |
|
| Sicherheit |
| P280 |
Schutzhandschuhe/Schutzkleidung/Augenschutz tragen. |
| P305+P351+P338 |
BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach Möglichkeit entfernen. Weiter spülen. |
|
Calcium levofolinate Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
L-Folinic acid is a reduced folic acid and isomer of DL-folinic acid . DL-Folinic acid is a racemic mixture of D-folinic acid and L-folinic acid that has been used to prevent toxicity following therapy with high-dose methotrexate , to enhance the antitumor activity of 5-fluorouracil , and as a folate supplement. Clinical studies demonstrate that formulations containing L-folinic acid have similar efficacy and tolerability as those contianing DL-folinic acid and have been used interchangeably for modification of antitumor activity of 5-fluorouracil, while D-folinic acid is inactive.
Chemische Eigenschaften
Off-White to Light Beige Amorphous Powder
Verwenden
Calcium levofolinate is a pharmaceutical drug that is used in biological studies for the treatment of colorectal cancer.
Calcium levofolinate Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Calcium levofolinate Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
Global( 241)Lieferanten
80433-71-2()Verwandte Suche:
- CALCIUM LEVOFOLINATE
- calcium n-(4-(((2-amino-5-formyl-1,4,5,6,7,8-hexahydro-4-oxo-6-pteridinyl)methyl)amino)benzoyl)-l-glutamate
- N-[4-[[(2-Amino-5-formyl-1,4,5,6,7,8-hexahydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-L-glutamic Acid Calcium Salt
- (S)-Leucovorin calcium salt (1:1)
- 5-Formyl-(6S)-tetrahydrofolate calcium salt
- Calcium (6S)-folinate
- CL 307782
- L-LEUCOVORIN CALCIUM
- Levofolinatecalcium
- Elvorine
- Isovorin
- L-Folinic acid calcium salt
- L-Glutamic acid, N-[4-[[(2-amino-5-formyl-1,4,5,6,7,8-hexahydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-, calcium salt (1:1), (S)-
- L-Glutamic acid, N-[4-[[[(6S)-2-amino-5-formyl-1,4,5,6,7,8-hexahydro-4-oxo-6-pteridinyl]methyl]amino]benzoyl]-, calcium salt (1:1) (9CI)
- levofolinic acid, calcium salt
- CalciuM levofolinate API
- Folinic Acid CalciuM (CalciuM Levofolinate)
- L-CalciuM Levofolinate
- N-[4-[[[(6S)-2-amino-5-formyl-3,4,5,6,7,8-hexahydro-4-oxo-6-pteridinyl]methyl]amino]benzoyl]-L-glutamic acid, calcium salt (1:1)
- l-Form calcium salt
- calcium (2S)-2-[[[4-[[(6S)-2-amino-5-formyl-4-oxo-1,6,7,8-tetrahydropteridin-6-yl]methylamino]phenyl]-oxomethyl]amino]pentanedioate
- (2S)-2-[[4-[(2-amino-5-formyl-4-oxo-1,6,7,8-tetrahydropteridin-6-yl)methylamino]benzoyl]amino]pentanedioate
- Levoleucovorin Calcium Pentahydrate (Calcium levofolinate
- (6S)-5-Formyl-5,6,7,8-tetrahydrofolic acid, calcium salt (natural calcium folinate)
- calcium,(2S)-2-[[4-[[(6S)-2-amino-5-formyl-4-oxo-1,6,7,8-tetrahydropteridin-6-yl]methylamino]benzoyl]amino]pentanedioate
- Calcium levofolinate USP/EP/BP
- Calcium Levofolinate ( Calcium levofolinate
- Calcium LevofolinateQ: What is
Calcium Levofolinate Q: What is the CAS Number of
Calcium Levofolinate Q: What is the storage condition of
Calcium Levofolinate Q: What are the applications of
Calcium Levofolinate
- L-Glutamic acid,N-[4-[[[(6S)-2-amino-5-formyl-1,4,5,6,7,8-hexahydro-4-oxo-6-pteridinyl]methyl]amino]benzoyl]-, calcium salt (1:1)
- levoleucovorin calcium
- levofolinate
- Calcium Levofolinate Pentahydrate
- Calcium leovate
- Levoleucovorin Calcium/Calcium levofolinate
- Levofolinate Calcium?Salt
- (4-((((S)-2-Amino-5-formyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl)methyl)amino)benzoyl)-L-glutamic acid, calcium salt(1:1)
- 2-[[4-[(2-amino-5-formyl-4-oxo-3,6,7,8-tetrahydropteridin-6-yl)methylamino]benzoyl]amino]pentanedioate
- calcium (S)-2-(4-((((S)-2-amino-5-formyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl)methyl)amino)benzamido)pentanedioate
- 80433-71-2
- C20H21N7O7Ca
- Inhibitors
- Intermediates & Fine Chemicals
- Pharmaceuticals
