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2-AMino-4-{4-chloro-2-[2-(4-fluoropyrazol-1-yl)ethoxy]-6-Methylphenyl}-5,7-dihydropyrrolo[3,4-d]pyriMidine-6-carboxylic acid (2,2-difluoropropyl)aMide

2-AMino-4-{4-chloro-2-[2-(4-fluoropyrazol-1-yl)ethoxy]-6-Methylphenyl}-5,7-dihydropyrrolo[3,4-d]pyriMidine-6-carboxylic acid (2,2-difluoropropyl)aMide Struktur
1207961-33-8
CAS-Nr.
1207961-33-8
Englisch Name:
2-AMino-4-{4-chloro-2-[2-(4-fluoropyrazol-1-yl)ethoxy]-6-Methylphenyl}-5,7-dihydropyrrolo[3,4-d]pyriMidine-6-carboxylic acid (2,2-difluoropropyl)aMide
Synonyma:
PF-494284;PF 04942847;2-Amino-4-(4-chloro-2-(2-(4-fluoro-1H-pyrazol-1-yl)ethoxy)-6-methylphenyl)-N-(2,2-difluoroprop;2-Amino-4-(4-chloro-2-(2-(4-fluoro-1H-pyrazol-1-yl)ethoxy)-6-methylphenyl)-N-(2,2-difluoropropyl);2-amino-4-[4-chloro-2-[2-(4-fluoropyrazol-1-yl)ethoxy]-6-methylphenyl]-N-(2,2-difluoropropyl)-5,7-dihydropyrrolo[3,4-d]pyrimidine-6-carboxamide;2-AMino-4-{4-chloro-2-[2-(4-fluoropyrazol-1-yl)ethoxy]-6-Methylphenyl}-5,7-dihydropyrrolo[3,4-d]pyriMidine-6-carboxylic acid (2,2-difluoropropyl)aMide;6H-Pyrrolo[3,4-d]pyrimidine-6-carboxamide, 2-amino-4-[4-chloro-2-[2-(4-fluoro-1H-pyrazol-1-yl)ethoxy]-6-methylphenyl]-N-(2,2-difluoropropyl)-5,7-dihydro-
CBNumber:
CB02609618
Summenformel:
C22H23ClF3N7O2
Molgewicht:
509.91
MOL-Datei:
1207961-33-8.mol
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2-AMino-4-{4-chloro-2-[2-(4-fluoropyrazol-1-yl)ethoxy]-6-Methylphenyl}-5,7-dihydropyrrolo[3,4-d]pyriMidine-6-carboxylic acid (2,2-difluoropropyl)aMide Eigenschaften

Sicherheit

2-AMino-4-{4-chloro-2-[2-(4-fluoropyrazol-1-yl)ethoxy]-6-Methylphenyl}-5,7-dihydropyrrolo[3,4-d]pyriMidine-6-carboxylic acid (2,2-difluoropropyl)aMide Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

A novel potent, selective, and orally bioavailable pyrrolodinopyrimidine-containing inhibitor of heat shock protein 90 (Hsp90). It has been shown to induce degradation of multiple client proteins, cell-cycle block, apoptosis, and inhibits cell proliferation in triple-negative breast cancer (TNBC) lines, subsequently leading to tumor growth inhibition in mouse xenograft models.

2-AMino-4-{4-chloro-2-[2-(4-fluoropyrazol-1-yl)ethoxy]-6-Methylphenyl}-5,7-dihydropyrrolo[3,4-d]pyriMidine-6-carboxylic acid (2,2-difluoropropyl)aMide Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

2-AMino-4-{4-chloro-2-[2-(4-fluoropyrazol-1-yl)ethoxy]-6-Methylphenyl}-5,7-dihydropyrrolo[3,4-d]pyriMidine-6-carboxylic acid (2,2-difluoropropyl)aMide Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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  • 2-AMino-4-{4-chloro-2-[2-(4-fluoropyrazol-1-yl)ethoxy]-6-Methylphenyl}-5,7-dihydropyrrolo[3,4-d]pyriMidine-6-carboxylic acid (2,2-difluoropropyl)aMide
  • PF-494284
  • 2-Amino-4-(4-chloro-2-(2-(4-fluoro-1H-pyrazol-1-yl)ethoxy)-6-methylphenyl)-N-(2,2-difluoropropyl)
  • 2-Amino-4-(4-chloro-2-(2-(4-fluoro-1H-pyrazol-1-yl)ethoxy)-6-methylphenyl)-N-(2,2-difluoroprop
  • 6H-Pyrrolo[3,4-d]pyrimidine-6-carboxamide, 2-amino-4-[4-chloro-2-[2-(4-fluoro-1H-pyrazol-1-yl)ethoxy]-6-methylphenyl]-N-(2,2-difluoropropyl)-5,7-dihydro-
  • PF 04942847
  • 2-amino-4-[4-chloro-2-[2-(4-fluoropyrazol-1-yl)ethoxy]-6-methylphenyl]-N-(2,2-difluoropropyl)-5,7-dihydropyrrolo[3,4-d]pyrimidine-6-carboxamide
  • 1207961-33-8
  • C22H23ClF3N7O2
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