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Clotiazepam

CLOTIAZEPAM Struktur
33671-46-4
CAS-Nr.
33671-46-4
Bezeichnung:
Clotiazepam
Englisch Name:
CLOTIAZEPAM
Synonyma:
Rise;Rize;Rizen;Clozan;Tienor;Y 6047;Trecalmo;Veratran;CLOTIAZEPAM;Rize-13C,d3
CBNumber:
CB0487933
Summenformel:
C16H15ClN2OS
Molgewicht:
318.82
MOL-Datei:
33671-46-4.mol

Clotiazepam Eigenschaften

Schmelzpunkt:
105-106°
Siedepunkt:
523.7±50.0 °C(Predicted)
Dichte
1.1625 (rough estimate)
Brechungsindex
1.6100 (estimate)
Löslichkeit
DMF: 15 mg/ml; DMSO: 15 mg/ml; DMSO:PBS (pH 7.2) (1:3): 0.25 mg/ml
Aggregatzustand
A crystalline solid
pka
2.36±0.20(Predicted)

Sicherheit

Toxizität LD50 in mice (mg/kg): 440 i.p., 636 orally (Nakanishi)

Clotiazepam Chemische Eigenschaften,Einsatz,Produktion Methoden

Chemische Eigenschaften

Off-White Solid

Verwenden

A thienodiazepine derivative that possesses anxiolytic, skeletal muscle relaxant anticonvulsant, sedative properties as well as contributing to siginificant increase stage 2 NREM sleep. It binds to be nzodiazepine site of the GABAA receptor where it acts as a full agonist resulting in enhanced GABA inhibitory effect at the GABAA receptor. Controlled Substance.

Clotiazepam Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Essigsure 5-(2-Chlorophenyl)-7-ethyl-1,3-dihydro-2H-thieno[2,3-e]-1,4-diazepin-2-one 2-(Aminoacetylamino)-3-(o-chlorobenzoyl)-5-ethylthiophene Methyljodid

Downstream Produkte

33671-46-4(Clotiazepam)Verwandte Suche:

1,4-Dihydro-2,6-dimethyl-4-(2-ni-trophenyl)-3,5-pyridindicarbon-säure-dimethylester Clotiazepam
  • CLOTIAZEPAM
  • 2H-Thieno(2,3-e)(1,4)diazepin-2-one, 1,3-dihydro-5-(o-chlorophenyl)-7-ethyl-1-methyl-
  • 2H-Thieno(2,3e)(1,4)-diazepin-2-one, 5-(o-chlorophenyl)-7-ethyl-1,3-dihydro-1-methyl-
  • 2h-thieno(2,3-e)(1,4)diazepin-2-one,1,3-dihydro-5-(o-chlorophenyl)-7-ethyl-1-m
  • 2h-thieno(2,3e)(1,4)-diazepin-2-one,5-(o-chlorophenyl)-7-ethyl-1,3-dihydro-1
  • 2H-Thieno[2,3-e]-1,4-diazepin-2-one, 5-(2-chlorophenyl)-7-ethyl-1,3-dihydro-1-methyl-
  • 2H-Thieno[2,3-E]-1,4-diazepine-2-one, 5-(2-chlorophenyl)-7-ethyl-1,3-dihydro-1-methyl-
  • 5-(2-chlorophenyl)-7-ethyl-1-methyl-1,3-dihydro-2h-thieno(2,3-e)(1,4)diazepi
  • 5-(2-Chlorophenyl)-7-ethyl-1-methyl-1,3-dihydro-2H-thieno(2,3-e)(1,4)diazepin-2-one
  • 5-(o-chlorophenyl)-7-ethyl-1,3-dihydro-1-methyl-2h-thieno(2,3-e)-1,4-diazepi
  • 5-(o-Chlorophenyl)-7-ethyl-1,3-dihydro-1-methyl-2H-thieno(2,3-e)-1,4-diazepin-2-one
  • Clozan
  • Rise
  • Rize
  • Rizen
  • Tienor
  • Trecalmo
  • Veratran
  • Y 6047
  • 2h-thieno(2,3-e)(1,4)diazepin-2-one,1,3-dihydro-5-(o-chlorophenyl)-7-et
  • 1-Methyl-5-o-chlorophenyl-7-ethyl-1,2-dihydro-3H-thieno[2,3-e][1,4]diazepin-2-one
  • 5-(o-Chlorophenyl)-7-ethyl-1-Methyl-1,2-dihydro-3H-thieno[2,3-e][1,4]diazep
  • 5-(o-Chlorophenyl)-7-ethyl-1-(Methyl-13C,d3)-1,2-dihydro-3H-thieno[2,3-e][1,4]diazepin-2-one
  • 5-(o-Chlorophenyl)-7-ethyl-1,3-dihydro-1-(Methyl-13C,d3)-2H-thieno[2,3-e]-1,4-diazepin-2-one
  • Clozan-13C,d3
  • Rize-13C,d3
  • Rizen-13C,d3
  • 5-(2-Chlorophenyl)-7-ethyl-1,3-dihydro-1-methyl-2H-thieno[2,3-e]-1,4-diazepin-2-one
  • 5-(2-chlorophenyl)-7-ethyl-1-methyl-3H-thieno[2,3-e][1,4]diazepin-2-one
  • Clotiazepam (1 mg/mL in Methanol)
  • CLOTIAZEPAM USP/EP/BP
  • 33671-46-4
  • Agonist
  • Aromatics
  • Heterocycles
  • Inhibitors
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • Sulfur & Selenium Compounds
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