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4-Amino-5-chloro-N-(1-((4-fluorophenyl)methyl)-4-piperidinyl)-2-methox ybenzamide

4-Amino-5-chloro-N-(1-((4-fluorophenyl)methyl)-4-piperidinyl)-2-methox ybenzamide Struktur
154540-49-5
CAS-Nr.
154540-49-5
Englisch Name:
4-Amino-5-chloro-N-(1-((4-fluorophenyl)methyl)-4-piperidinyl)-2-methox ybenzamide
Synonyma:
fluoroclebopride;Inhibitor,inhibit,Fluoroclebopride,Dopamine Receptor;4-Amino-5-chloro-N-(1-((4-fluorophenyl)methyl)-4-piperidinyl)-2-methox ybenzamide;Benzamide,4-amino-5-chloro-N-[1-[(4-fluorophenyl)methyl]-4-piperidinyl]-2-methoxy-
CBNumber:
CB11242925
Summenformel:
C20H23ClFN3O2
Molgewicht:
391.87
MOL-Datei:
154540-49-5.mol
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4-Amino-5-chloro-N-(1-((4-fluorophenyl)methyl)-4-piperidinyl)-2-methox ybenzamide Eigenschaften

Siedepunkt:
518.2±50.0 °C(Predicted)
Dichte
1.31±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
Löslichkeit
DMF: 20 mg/ml; DMF:PBS (pH 7.2) (1:9): 0.1 mg/ml; DMSO: 10 mg/ml; Ethanol: 10 mg/ml
Aggregatzustand
A crystalline solid
pka
13.62±0.20(Predicted)
Farbe
White to off-white

Sicherheit

4-Amino-5-chloro-N-(1-((4-fluorophenyl)methyl)-4-piperidinyl)-2-methox ybenzamide Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Fluoroclebopride is a benzamide analog that is used in positron emission tomography (PET) applications. It binds reversibly to dopamine receptors (Kis = 0.95, 5.7, 5.46, and 144 nM for D2-like, D2(long), D3, and D4 receptors, respectively, in radioligand binding assays). It is selective for these receptors over D1, serotonin 5-HT2, and α2-adrenergic receptors (Kis = >10,000, 283, and 1,300 nM, respectively). A fluorine-18 moiety has been used to label this compound for use as a probe for studying D2/D3 receptor availability via PET in various monkey models.

4-Amino-5-chloro-N-(1-((4-fluorophenyl)methyl)-4-piperidinyl)-2-methox ybenzamide Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

4-Amino-5-chloro-N-(1-((4-fluorophenyl)methyl)-4-piperidinyl)-2-methox ybenzamide Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 42)Lieferanten
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ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795
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  • 4-Amino-5-chloro-N-(1-((4-fluorophenyl)methyl)-4-piperidinyl)-2-methox ybenzamide
  • fluoroclebopride
  • Benzamide,4-amino-5-chloro-N-[1-[(4-fluorophenyl)methyl]-4-piperidinyl]-2-methoxy-
  • Inhibitor,inhibit,Fluoroclebopride,Dopamine Receptor
  • 154540-49-5
  • C20H23ClFN3O2
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