EO 1428

EO 1428 Struktur
321351-00-2
CAS-Nr.
321351-00-2
Englisch Name:
EO 1428
Synonyma:
EO 1428;p38 MAPK Inhibitor VIII;p38 MAP Kinase Inhibitor VIII;(2-Methylphenyl)-[4-[(2-amino-4-bromophenyl)amino]-2-chlorophenyl]methanone;Methanone, [4-[(2-amino-4-bromophenyl)amino]-2-chlorophenyl](2-methylphenyl)-
CBNumber:
CB12455755
Summenformel:
C20H16BrClN2O
Molgewicht:
415.71
MOL-Datei:
321351-00-2.mol

EO 1428 Eigenschaften

storage temp. 
Store at +4°C
Löslichkeit
Soluble to 100 mM in DMSO and to 50 mM in ethanol
Aggregatzustand
Powder

Sicherheit

EO 1428 Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

EO 1428 is a p38 MAP kinase inhibitor with high antiinflammatory activity.

Biologische Aktivität

Selective inhibitor of p38 α and p38 β 2 that displays no activity at p38 γ , p38 δ , ERK1/2 and JNK1. Inhibits production of inflammatory cytokines including IL-8, TNF- α , IL-6, IL-1 β and IL-10 (IC 50 values are 4, 5, 17, 30 and 74 nM respectively). Displays anti-inflammatory activity in murine models of acute and chronic dermatitis.

EO 1428 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


EO 1428 Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 26)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000
marketing@targetmol.com United States 19892 58
Hangzhou MolCore BioPharmatech Co.,Ltd.
+86-057181025280; +8617767106207
sales@molcore.com China 49739 58
Aladdin Scientific
+1-+1(833)-552-7181
sales@aladdinsci.com United States 52927 58
3B Pharmachem (Wuhan) International Co.,Ltd. 821-50328103-801 18930552037
3bsc@sina.com China 15848 69
EMMX Biotechnology LLC 888-539-0666
info@emmx.com United States 8449 60
MedBioPharmaceutical Technology Inc 021-69568360 18916172912
order@med-bio.cn China 8141 58
Jinan Jiuli Biotechnology Co. , Ltd. 15865264761
486064515@qq.com China 3383 58
TargetMol Chemicals Inc. 4008200310
marketing@tsbiochem.com China 24647 58
Nantong QuanYi Biotechnology Co., Ltd 0513-66337626 18051384581
sales@chemhifuture.com China 4738 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627
customer_service@efebio.com China 11975 58

  • p38 MAP Kinase Inhibitor VIII
  • EO 1428
  • (2-Methylphenyl)-[4-[(2-amino-4-bromophenyl)amino]-2-chlorophenyl]methanone
  • p38 MAPK Inhibitor VIII
  • Methanone, [4-[(2-amino-4-bromophenyl)amino]-2-chlorophenyl](2-methylphenyl)-
  • 321351-00-2
  • C20H16BrClN2O
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