4-(4-(1,3,4-thiadiazol-2-yl)piperazin-1-yl)-6-ethylthieno[2,3-d]pyriMidine

4-(4-(1,3,4-thiadiazol-2-yl)piperazin-1-yl)-6-ethylthieno[2,3-d]pyriMidine Struktur
1359873-35-0
CAS-Nr.
1359873-35-0
Englisch Name:
4-(4-(1,3,4-thiadiazol-2-yl)piperazin-1-yl)-6-ethylthieno[2,3-d]pyriMidine
Synonyma:
4-(4-(1,3,4-thiadiazol-2-yl)piperazin-1-yl)-6-ethylthieno[2,3-d]pyriMidine;6-Ethyl-4-[4-(1,3,4-thiadiazol-2-yl)-1-piperazinyl]thieno[2,3-d]pyrimidine;Thieno[2,3-d]pyrimidine, 6-ethyl-4-[4-(1,3,4-thiadiazol-2-yl)-1-piperazinyl]-
CBNumber:
CB12582671
Summenformel:
C14H16N6S2
Molgewicht:
332.45
MOL-Datei:
1359873-35-0.mol

4-(4-(1,3,4-thiadiazol-2-yl)piperazin-1-yl)-6-ethylthieno[2,3-d]pyriMidine Eigenschaften

Siedepunkt:
535.8±60.0 °C(Predicted)
Dichte
1.410±0.06 g/cm3(Predicted)
storage temp. 
Refrigerator, under inert atmosphere
Löslichkeit
Chloroform; Dichloromethane; Methanol;
pka
5.24±0.40(Predicted)
Aggregatzustand
Solid
Farbe
Off-white

Sicherheit

4-(4-(1,3,4-thiadiazol-2-yl)piperazin-1-yl)-6-ethylthieno[2,3-d]pyriMidine Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

6-Ethyl-4-[4-(1,3,4-thiadiazol-2-yl)-1-piperazinyl]thieno[2,3-d]pyrimidine is an intermediate used in the synthesis of 6-Ethyl-4-[4-(1,3,4-thiadiazol-2-yl)-1-piperazinyl]thieno[2,3-d]pyrimidine Hydrochloride (E926745), which is an inhibitor of fusion protein interaction of menin-mixed lineage leukemia (menin-MLL). Menin-MLL inhibitors downregulate the expression of target genes required for MLL fusion protein oncogenic activity and thus effectively reverse MLL fusion protein-mediated leukemic transformation.

4-(4-(1,3,4-thiadiazol-2-yl)piperazin-1-yl)-6-ethylthieno[2,3-d]pyriMidine Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


4-(4-(1,3,4-thiadiazol-2-yl)piperazin-1-yl)-6-ethylthieno[2,3-d]pyriMidine Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 5)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Yancheng KangdiSen Pharmaceutical Co., Ltd. 13812573443
tongbenwan22@163.com China 1982 55
Wuxi KaideRui Pharmaceutical Technology Co., Ltd 19906241957
1557216087@qq.com China 1768 55
Wuxi Donghe Pharmaceutical Technology Co., Ltd. 63313187 15358055255
63313187@qq.com China 1995 58

  • 4-(4-(1,3,4-thiadiazol-2-yl)piperazin-1-yl)-6-ethylthieno[2,3-d]pyriMidine
  • Thieno[2,3-d]pyrimidine, 6-ethyl-4-[4-(1,3,4-thiadiazol-2-yl)-1-piperazinyl]-
  • 6-Ethyl-4-[4-(1,3,4-thiadiazol-2-yl)-1-piperazinyl]thieno[2,3-d]pyrimidine
  • 1359873-35-0
  • C14H16N6S2
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