Prostaglandin E2-d9 Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
PGE
2-
d
9 contains nine deuterium atoms at the 17, 17’, 18, 18’, 19, 19'', 20, 20, and 20'' positions. It is intended for use as an internal standard for the quantification of PGE
2 by GC-
or LC-
mass spectrometry (MS). PGE
2 is one of the primary cyclooxygenase products of arachidonic acid and one of the most widely investigated prostaglandins. Its activity influences inflammation, fertility and parturition, gastric mucosal integrity, and immune modulation. The effects of PGE
2 are transduced by at least four distinct receptors designated EP
1, EP
2, EP
3, and EP
4. Affinity constants (K
d) of PGE
2 for these receptors range from 1-
10 nM depending on the receptor subtype and tissue.
Prostaglandin E2-d9 Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
