NAJA NAJA OXIANA NEUROTOXIN II

NAJA NAJA OXIANA NEUROTOXIN II Struktur
60318-11-8
CAS-Nr.
60318-11-8
Englisch Name:
NAJA NAJA OXIANA NEUROTOXIN II
Synonyma:
nt-ii;Snake toxin;NAJA NAJA OXIANA TOXIN;neurotoxinii,najanajaoxiana;neurotoxinii(najanajaoxiana);NAJA NAJA OXIANA NEUROTOXIN II;toxin snake from naja naja oxiana;Neurotoxin I from Naja naja oxiana;Neurotoxin II from Naja naja oxiana
CBNumber:
CB1259669
Summenformel:
C283H443N93O92S8
Molgewicht:
6876.63342
MOL-Datei:
60318-11-8.mol

NAJA NAJA OXIANA NEUROTOXIN II Eigenschaften

storage temp. 
2-8°C

Sicherheit

RTECS-Nr. QQ4497475

NAJA NAJA OXIANA NEUROTOXIN II Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

The snake toxin is one of a family of small neurotoxic proteins (MW ~ 8,000 Da) isolated from the venom of elapid snakes (cobras and their relatives). α-Bungarotoxin also binds to certain insect nAChRs (8,9), although a separate α-bungarotoxin–insensitive class of nAChR has been found in some species (9).

Verwenden

The snake toxin, α-bungarotoxin, has been used extensively to characterize vertebrate nAChRs because it selectively binds to certain populations of vertebrate receptors.

Pharmakologie

The snake toxin binds very tightly to the receptor and competitively blocks the binding of acetylcholine; consequently, radiolabeled α-bungarotoxin has been used to design competitive binding assays to measure the in vitro potencies of competitive ligands such as the neonicotinoids. However, no information concerning the agonist or antagonist nature of test compounds is obtained using these methods. Binding studies using both α-bungarotoxin and imidacloprid have indicated that some insect receptors that do not bind α- bungarotoxin with high affinity do bind imidacloprid (10). Such bungarotoxin-insensitive nicotinic receptors have also been identified using electrophysiology (11).

NAJA NAJA OXIANA NEUROTOXIN II Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


NAJA NAJA OXIANA NEUROTOXIN II Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 2)Lieferanten
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