A 40926 coMplex Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
Parvodicin complex is a mixture of closely related lipophilic glycopeptides originally isolated from
A. parvosata. The parvodicin complex has activity against Gram-positive bacteria (MICs = 0.8-12.5 μg/ml) including methicillin-resistant strains of
S. aureus (MRSA),
S. hemolyticus, and
E. faecalis (MICs = 0.1-25 μg/ml). Glycopeptide antibiotics act by preventing cell wall synthesis by binding and sequestering a cell wall precursor with a D-alanine-containing peptide.
Verwenden
Parvodicin complex is a family of glycopeptides with potent antibiotic activity, isolated from Actinomadura parvosata. Structurally the parvodicins share a common cyclic peptide core with ristocetin. The analogues within the complex vary in the fatty acid substitution on the aminosugar. Like other glycopeptides in this class, parvodicin complex inhibits cell wall formation by binding to D-alanine-D-alanine residues. Parvodicin complex is a precursor to the synthetic glycopepide, dalbavancin.
A 40926 coMplex Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
