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RO-31-7549

RO-31-7549 Struktur
125313-65-7
CAS-Nr.
125313-65-7
Englisch Name:
RO-31-7549
Synonyma:
RO-31-7549;RO 31-7549 ACETATE SALT;Bisindolylmaleimide VIII;BISINDOLYLMALEIMIDE VIII ACETATE;BIDINDOLYLMALEIMIDE VIII, ACETETE;Ro-31-7549, Monohydrate - CAS 125313-65-7 - Calbiochem;2-[1-3(AMINOPROPYL)INDOL-3-YL]-3(1-METHYL-1H-INDOL-3-YL)MALEIMIDE, ACETATE;3-(1-(3-Aminopropyl)-1H-indol-3-yl)-4-(1-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione;1H-Pyrrole-2,5-dione, 3-(1-(3-aminopropyl)-1H-indol-3-yl)-4-(1-methyl-1H-indol-3-yl)-
CBNumber:
CB1281637
Summenformel:
C24H22N4O2
Molgewicht:
398.46
MOL-Datei:
125313-65-7.mol
Request For Quotation

RO-31-7549 Eigenschaften

storage temp. 
−20°C
Löslichkeit
DMSO: soluble
Aggregatzustand
Red to reddish-orange solid

Sicherheit

WGK Germany  3

RO-31-7549 Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

It is a potent inhibitor of protein kinase C (PKC) activity.

Allgemeine Beschreibung

A cell permeable, reversible, selective protein kinase C (PKC) inhibitor (IC50 = 158 nM for rat brain PKC) that acts at the ATP binding site of PKC. Does not inhibit the tyrosine phosphorylation or the activation of phospholipase Cγ1. Exhibits some degree of PKC isozyme specificity (IC50 = 53 nM for PKCα, 195 nM for PKCβI, 163 nM for PKCβII, 213 nM for PKCγ, and 175 nM for PKCε). Inhibits carbachol-evoked noradrenaline release (IC50 = 600 nM).

Biochem/physiol Actions

Cell permeable: yes

RO-31-7549 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

RO-31-7549 Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 40)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000
 marketing@targetmol.com United States 32165 58
Hangzhou MolCore BioPharmatech Co.,Ltd. 		+86-057181025280; +8617767106207
 sales@molcore.com China 49734 58
J & K SCIENTIFIC LTD. 010-82848833 400-666-7788
 jkinfo@jkchemical.com China 96815 76
Chemsky (shanghai) International Co.,Ltd 021-50135380
shchemsky@sina.com China 15402 60
Sigma-Aldrich 021-61415566 800-8193336
 orderCN@merckgroup.com China 51456 80
Shenzhen Polymeri Biochemical Technology Co., Ltd. +86-400-002-6226 +86-13028896684;
 sales@rrkchem.com China 57412 58
Energy Chemical 021-58432009 400-005-6266
 marketing1@energy-chemical.com China 44808 58
TargetMol Chemicals Inc. 4008200310
 marketing@tsbiochem.com China 24647 58
  • BISINDOLYLMALEIMIDE VIII ACETATE
  • 1H-Pyrrole-2,5-dione, 3-(1-(3-aminopropyl)-1H-indol-3-yl)-4-(1-methyl-1H-indol-3-yl)-
  • 3-(1-(3-Aminopropyl)-1H-indol-3-yl)-4-(1-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione
  • Bisindolylmaleimide VIII
  • 2-[1-3(AMINOPROPYL)INDOL-3-YL]-3(1-METHYL-1H-INDOL-3-YL)MALEIMIDE, ACETATE
  • RO-31-7549
  • RO 31-7549 ACETATE SALT
  • BIDINDOLYLMALEIMIDE VIII, ACETETE
  • Ro-31-7549, Monohydrate - CAS 125313-65-7 - Calbiochem
  • 125313-65-7
  • C24H22N4O2C2H4O2
  • Amines
  • Aromatics
  • Heterocycles
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • Protein Kinase Inhibitors and Activators
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