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5-Methyluridin

5-Methyluridine Struktur
1463-10-1
CAS-Nr.
1463-10-1
Bezeichnung:
5-Methyluridin
Englisch Name:
5-Methyluridine
Synonyma:
RIBOTHYMIDINE;1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxyMethyl)tetrahydrofuran-2-yl)-5-MethylpyriMidine-2,4(1H,3H)-dione;1-(BETA-D-RIBOFURANOSYL)THYMINE;5-Me-U;5-Me-Ur;Methyluridine;5-methyuridine;ribosylthymine;5-methyl-uridin;THYMINERIBOSIDE
CBNumber:
CB1322473
Summenformel:
C10H14N2O6
Molgewicht:
258.23
MOL-Datei:
1463-10-1.mol
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5-Methyluridin Eigenschaften

Schmelzpunkt:
183-184 °C(lit.)
Dichte
1.576±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
Löslichkeit
Methanol (Slightly, Heated, Sonicated), Water (Sparingly, Sonicated)
pka
9.55±0.10(Predicted)
Aggregatzustand
powder
Farbe
white
PH
9.7
maximale Wellenlänge (λmax)
267 (pH 1)；268 (pH 13)
InChI
InChI=1S/C10H14N2O6/c1-4-2-12(10(17)11-8(4)16)9-7(15)6(14)5(3-13)18-9/h2,5-7,9,13-15H,3H2,1H3,(H,11,16,17)/t5-,6-,7-,9-/m1/s1
InChIKey
DWRXFEITVBNRMK-JXOAFFINSA-N
SMILES
OC[C@H]1O[C@@H](N2C=C(C)C(=O)NC2=O)[C@H](O)[C@@H]1O
CAS Datenbank
1463-10-1(CAS DataBase Reference)
Sicherheit
  • Risiko- und Sicherheitserklärung
  • Gefahreninformationscode (GHS)
Kennzeichnung gefährlicher T+
R-Sätze: 26/27/28
S-Sätze: 24/25
WGK Germany  3
HS Code  29349990
Bildanzeige (GHS) GHS hazard pictograms
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H302 Gesundheitsschädlich bei Verschlucken. Akute Toxizität oral Kategorie 4 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P270, P301+P312, P330, P501
H315 Verursacht Hautreizungen. Hautreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P302+P352, P321,P332+P313, P362
H319 Verursacht schwere Augenreizung. Schwere Augenreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P305+P351+P338,P337+P313P
H335 Kann die Atemwege reizen. Spezifische Zielorgan-Toxizität (einmalige Exposition) Kategorie 3 (Atemwegsreizung) Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" />
Sicherheit
P261 Einatmen von Staub vermeiden.
P305+P351+P338 BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach Möglichkeit entfernen. Weiter spülen.

5-Methyluridin Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:

R26/27/28:Sehr giftig beim Einatmen, Verschlucken und Berührung mit der Haut.

S-Sätze Betriebsanweisung:

S24/25:Berührung mit den Augen und der Haut vermeiden.

Beschreibung

5-Methyluridine is a pyrimidine nucleoside and methylated form of uridine. It is the ribonucleoside counterpart to the deoxyribonucleoside thymidine, which lacks a hydroxyl group at the 2' position. 5-Methyluridine contains a thymine base joined to a ribose pentose sugar. It is an endogenous methylated nucleoside found in human fluids. In cells, 5-methyluridine is present in tRNA, formed during its post-transcriptional modification by the methylation of uridine.

Chemische Eigenschaften

White Powder

Verwenden

A primary degradation product of tRNA, an urinary nucleoside as biological marker for patients with colorectal cancer.
It enhances the antitumor activity of 5-fluorouracil in a mouse Erlich solid carcinoma model and a P388 murine leukemia model. It has been used to characterize the activity of a variety of enzymes, including uridine nucleosidase.

5-Methyluridin Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Uridine, 5'-O-[(4-methoxyphenyl)diphenylmethyl]-5-methyl- (9CI) Uridine, 5-methyl-5'-O-(triphenylmethyl)- Uridine, 5-methyl-, 2',3',5'-triacetate Uridine, 5-methyl-, 2',3',5'-tribenzoate 2'-O-[2-[(diMethylaMino)oxy]ethyl]-5-Methyl-uridine 1-O-Acetyl-2,3,5-tri-O-benzoyl-β-D-ribofuranose 1,2,3,5-TETRA-O-ACETYL-BETA-L-RIBOFURANOSE N3-Methyl-5-methyluridine BIS(O-TRIMETHYLSILYL)THYMINE Triethylammoniumfluorid 5-Methyluracil Guanosine

Downstream Produkte

1-β-D-Arabinofuranosyl-5-methyl-(1H,3H)-pyrimidin-2,4-dion Ethylbenzoat Stavudine

5-Methyluridin Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 455)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Wuhu Nuowei chemistry Co., Ltd.
+86-0553-2911116-802 +undefined17756524438
 sales1@nuowei-chem.com China 1638 58
Xinxiang Aurora Biotechnology Co.,Ltd.
+86-0086-0373-3088722 +8618637352520
 info@aurora-biotech.com China 91 58
Shaanxi Dideu Medichem Co. Ltd 		+86-29-81148696 +86-15536356810
 1022@dideu.com China 3882 58
Hebei Mojin Biotechnology Co., Ltd 		+86 13288715578 +8613288715578
 sales@hbmojin.com China 12835 58
Hebei Weibang Biotechnology Co., Ltd 		+8617732866630
 bess@weibangbio.com China 18155 58
Capot Chemical Co.,Ltd. 		+86-（0）57185586718 +86-13336195806
 sales@capot.com China 29791 60
Shanghai Daken Advanced Materials Co.,Ltd 		+86-371-66670886
info@dakenam.com China 18754 58
Shanghai Time Chemicals CO., Ltd. 		+86-021-57951555 +8617317452075
 jack.li@time-chemicals.com China 1803 55
Hangzhou FandaChem Co.,Ltd. 		+8615858145714
 FandaChem@Gmail.com China 9218 55
Shanghai Zheyan Biotech Co., Ltd. 		18017610038
zheyansh@163.com CHINA 3619 58

1463-10-1(5-Methyluridin)Verwandte Suche:

5-Methyluridin
  • 5-methyl-uridin
  • 5-methyuridine
  • 5-Methyluridine (Patent )
  • THYMINERIBOSIDE
  • URIDINE, 5-METHYL-
  • 5-METHYLURIDINE(5-Methyl-1-ˉ-ribofuranosyl uracil
  • 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione
  • 5-methyluridine/ribothymidine
  • ribosylthymine/5-methyluridine
  • Methyluridine
  • 5-Me-U
  • 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxyMethyl)oxolan-2-yl]-5-Methyl-1,2,3,4-tetrahydropyriMidine-2,4-dione
  • RibosylthyMine(5-Methyluridine,RibothyMidine)
  • 1-β-D-Ribofuranosylthymine
  • 5-Methyl-1-β-D-ribofuranosyl-1,2,3,4-tetrahydropyrimidine-2,4-dione
  • 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-methylol-tetrahydrofuran-2-yl]-5-methyl-pyrimidine-2,4-quinone
  • 5-Methyluridine, >=99%
  • 5-Methyluridine≥ 99% (HPLC)
  • 5-METHYLURIDINE
  • 5-METHYL-D-URIDINE
  • 5-METHYL-1-BETA-D-RIBOFURANOSYL URACIL
  • 1-(BETA-D-RIBOFURANOSYL)THYMIDINE
  • BETA-D-THYMINE RIBOSIDE
  • BETA-RIBOFURANOSIDE
  • ribosylthymine
  • 5-methyluridine (produced by synthesis)
  • 5-Me-Ur
  • 5-Methyluridine>
  • 5-Methyluridine USP/EP/BP
  • 5-Methyluridine extrapure, 98%
  • 1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxyMethyl)tetrahydrofuran-2-yl)-5-MethylpyriMidine-2,4(1H,3H)-dione
  • 1-(BETA-D-RIBOFURANOSYL)THYMINE
  • RIBOTHYMIDINE
  • 5-Methyluridine, RNA modified ribo-nucleoside m5U
  • 5-Methyfuridine
  • 1463-10-1
  • 1436-10-1
  • 1463-10-3
  • C10H14N2O6
  • Specialty Synthesis
  • Nucleosides
  • Oligonucleotide Synthesis
  • Nucleosides, Nucleotides, Oligonucleotides
  • Nucleoside Analogs
  • BioChemical
  • Biochemicals and Reagents
  • Carbohydrates & Derivatives
  • Heterocycles
  • Biochemistry
  • Nucleosides and their analogs
  • Nucleosides, Nucleotides & Related Reagents
  • Bases & Related Reagents
  • Nucleotides
  • Pyridines, Pyrimidines, Purines and Pteredines
  • Miscellaneous Biochemicals
  • Nucleotides and Nucleosides
  • bc0001
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