ANTI-MCL-1
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- CAS-Nr.
- Englisch Name:
- ANTI-MCL-1
- Synonyma:
- Anti-TM;Anti-EAT;mcl1/EAT;Anti-MCI1;EAT/MCL-1;Anti-MCL1L;Anti-MCL1S;ANTI-MCL-1;Anti-APOER2;Anti-BCL2L3
- CBNumber:
- CB1338751
- Summenformel:
- Molgewicht:
- 0
- MOL-Datei:
- Mol file
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ANTI-MCL-1 Eigenschaften
- storage temp.
- −20°C
- Aggregatzustand
- buffered aqueous solution
Sicherheit
- Risiko- und Sicherheitserklärung
- Gefahreninformationscode (GHS)
| Bildanzeige (GHS) |
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| Alarmwort |
Warnung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H412 |
Schädlich für Wasserorganismen, mit langfristiger Wirkung. |
Langfristig (chronisch) gewässergefährdend |
Kategorie 3 |
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P273, P501 |
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| Sicherheit |
| P273 |
Freisetzung in die Umwelt vermeiden. |
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ANTI-MCL-1 Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Immunocytochemistry (1 paper)Immunohistochemistry (1 paper)
Allgemeine Beschreibung
Induced myeloid leukemia cell differentiation protein Mcl-1(MCL1) belongs to the Bcl-2 family and contains the characteristic Bcl-2 homology (BH) domain. The gene encoding this protein is present on chromosome 1q21.
Biochem/physiol Actions
Induced myeloid leukemia cell differentiation protein Mcl-1(MCL1) plays an important role in inhibiting apoptosis and is expressed only during particular stages of cell differentiation and in response to specific signals. It is a viability-promoting protein that interacts with fortilin (an anti-apoptotic protein) and regulates cell viability. Specific differentiation- and apoptosis-inducing stimuli enhance the expression of this protein. MCL1 acts as a chaperone of fortilin by binding and stabilizing it. It also interacts and negatively regulates the proliferating cell nuclear antigen (PCNA), which a cell cycle-regulatory protein essential for G1 to S phase transition. Hence, it functions to retard the cell cycle progression.
ANTI-MCL-1 Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
ANTI-MCL-1 Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
Global( 20)Lieferanten
- ANTI-MCL-1 (HUMAN)
- ANTI-MCL-1(K-20)
- ANTI-MCL-1(S-19)
- ANTI-HUMAN MCL-1
- MCL-1 (AB-1) MONOCLONAL ANTIBODY
- RABBIT ANTI-HUMAN MCL-1
- Anti-Mcl-1 antibody produced in rabbit
- Anti-Bcl-2-related protein EAT/mcl1 antibody produced in rabbit
- Anti-Induced myeloid leukemia cell differentiation protein Mcl-1 antibody produced in rabbit
- Anti-mcl1/EAT antibody produced in rabbit
- Anti-APOER2
- Anti-HSZ75190
- Anti-LRP8 antibody produced in rabbit
- Anti-MCI1
- Anti-BCL2L3
- Anti-myeloid cell leukemia sequence 1 (BCL2-related)
- Anti-OTTHUMG00000024149
- Anti-EAT
- Anti-MCL1 (186-200) antibody produced in rabbit
- Anti-MCL1L
- Anti-MCL1S
- Bcl-2-related protein EAT/mcl1
- EAT/MCL-1
- induced myeloid leukemia cell differentiation protein Mcl-1
- mcl1/EAT
- myeloid cell leukemia sequence 1
- Anti-MCL1 (Isoform 1) antibody produced in goat
- Anti-MGC1839
- Anti-TM
- Anti-low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
- ANTI-MYELOID CELL LEUKEMIA-1 (HUMAN)
- ANTI-MCL-1
- ANTI-MCL-1 (AB-1), HUMAN
- ANTI-MCL-1 (AB-1) MOUSE MAB
- ANTI-APOER2
- Myeloid Cell Leukemia-1 (Mcl-1)Alphabetical Index
- Antibodies for Kinase/Phosphatase Biology
- M
- Other
- Serine/Threonine Kinase Adaptor Protein Antibodies
