TYRPHOSTIN B7

134036-53-6

CAS-Nr.: 134036-53-6

Englisch Name:: TYRPHOSTIN B7

Synonyma:: AG 370;TYRPHOSTIN B7;TYRPHOSTIN AG 370;TYROPHOSTIN AG 370;2-AMINO-4-(1H-INDOL-5-YL)-1,1,3-TRICYANOBUTA-1,3-DIENE;2-AMINO-4-(1H-INDO-5'-YL)-1,1,3-TRICYANOBUTA-1,3-DIENE;3-AMINO-4-(1H-INDOL-5-YLMETHYLENE)-2-PENTENETRICARBONITRILE;2-Pentenetricarbonitrile, 3-amino-4-(1H-indol-5-ylmethylene)-;2-Amino-4-(1H-indo-5μ-yl)-1,1,3-tricyanobuta-1,3-diene, Tyrphostin B7

CBNumber:: CB2288901

Summenformel:: C15H9N5

Molgewicht:: 259.27

MOL-Datei:: 134036-53-6.mol

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Eigenschaften Sicherheit Verwendungswort Produktionsfirma 36

TYRPHOSTIN B7 Eigenschaften

Siedepunkt:: 714.1±60.0 °C(Predicted)

Dichte: 1.396±0.06 g/cm3(Predicted)

storage temp.: −20°C

Löslichkeit: DMSO: soluble

pka: 15.95±0.30(Predicted)

Aggregatzustand: Yellow solid.

Sicherheit

S-Sätze:	22-24/25
WGK Germany	3

TYRPHOSTIN B7 Chemische Eigenschaften,Einsatz,Produktion Methoden

S-Sätze Betriebsanweisung:

S22:Staub nicht einatmen.
S24/25:Berührung mit den Augen und der Haut vermeiden.

Beschreibung

Protein tyrosine kinase (PTK) inhibitors are potential antiproliferative agents for diseases caused by the hyperactivity of PTKs. Tyrphostins are a class of antiproliferative compounds which selectively inhibit PTKs of key growth factors such as epidermal growth factor (EGF) or platelet-derived growth factor (PDGF) by blocking the phosphorylation of specific tyrosine residues. AG-370 is a selective inhibitor of PDGF receptor kinase with an IC₅₀ value of 20 μM in human bone marrow fibroblasts. It displays comparatively weak inhibition of the EGF receptor (IC₅₀ = 820 μM).

TYRPHOSTIN B7 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

TYRPHOSTIN B7 Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 36)Lieferanten

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
Aladdin Scientific	+1-+1(833)-552-7181	sales@aladdinsci.com	United States	52925	58
3B Pharmachem (Wuhan) International Co.,Ltd.	821-50328103-801 18930552037	3bsc@sina.com	China	15839	69
Spectrum Chemical Manufacturing Corp.	021-021-021-67601398-809-809-809 15221380277	marketing_china@spectrumchemical.com	China	9658	60
BOC Sciences	16314854226	info@bocsci.com	United States	9923	65
Shanghai EFE Biological Technology Co., Ltd.	021-65675885 18964387627	info@efebio.com	China	9806	58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.	18818260767	sales@chemegen.com	China	11217	58
MedBioPharmaceutical Technology Inc	021-69568360 18916172912	order@med-bio.cn	China	8140	58
TargetMol Chemicals Inc.	4008200310	marketing@tsbiochem.com	China	24647	58
ApexBio Technology	--	sales@apexbt.com	United States	6251	58

134036-53-6()Verwandte Suche:

[(4-Hydroxyphenyl)methylen]malononitril 3-Aminoprop-1-en-1,1,3-tricarbonitril 3-Butennitril

AG 370
2-Amino-4-(1H-indo-5μ-yl)-1,1,3-tricyanobuta-1,3-diene, Tyrphostin B7
TYROPHOSTIN AG 370
TYRPHOSTIN B7
TYRPHOSTIN AG 370
3-AMINO-4-(1H-INDOL-5-YLMETHYLENE)-2-PENTENETRICARBONITRILE
2-AMINO-4-(1H-INDO-5'-YL)-1,1,3-TRICYANOBUTA-1,3-DIENE
2-AMINO-4-(1H-INDOL-5-YL)-1,1,3-TRICYANOBUTA-1,3-DIENE
2-Pentenetricarbonitrile, 3-amino-4-(1H-indol-5-ylmethylene)-
134036-53-6
Platelet Derived Growth Factor Receptor (PDGFR)
Receptor Tyrosine Kinase Inhibitors
Kinase/Phosphatase Biology
Cell Signaling and Neuroscience
Cell Biology
BioChemical