2-Aminoadenosine

2-Aminoadenosine  Struktur
2096-10-8
CAS-Nr.
2096-10-8
Englisch Name:
2-Aminoadenosine
Synonyma:
2-NH2-A;Aminoadenosine;2-AMINE ADENOSINE;2,6-DIAMINOPURINE RIBOSIDE;0/8/96;NSC 7363;2-NH2-Ar;2-NH2-rA;2-NH?-rA;2-AMinoadenosin
CBNumber:
CB2468756
Summenformel:
C10H14N6O4
Molgewicht:
282.26
MOL-Datei:
2096-10-8.mol

2-Aminoadenosine Eigenschaften

Schmelzpunkt:
241-243°C (dec.)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
Löslichkeit
Aqueous Acid (Slightly, Heated, Sonicated), DMSO (Slightly, Sonicated), Ethanol
Aggregatzustand
Powder
Siedepunkt:
798.5±70.0 °C(Predicted)
Dichte
2.25±0.1 g/cm3(Predicted)
pka
13.10±0.70(Predicted)
Farbe
White to Off-White
InChIKey
ZDTFMPXQUSBYRL-UUOKFMHZSA-N
CAS Datenbank
2096-10-8(CAS DataBase Reference)
Sicherheit
  • Risiko- und Sicherheitserklärung
  • Gefahreninformationscode (GHS)
S-Sätze: 24/25
HS Code  29389090
Bildanzeige (GHS) GHS hazard pictograms
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H315 Verursacht Hautreizungen. Hautreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P302+P352, P321,P332+P313, P362
H319 Verursacht schwere Augenreizung. Schwere Augenreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P305+P351+P338,P337+P313P
Sicherheit
P264 Nach Gebrauch gründlich waschen.
P264 Nach Gebrauch gründlich waschen.
P280 Schutzhandschuhe/Schutzkleidung/Augenschutz tragen.

2-Aminoadenosine Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

2-Aminoadenosine is a known analogue of adenosine that engages in three hydrogen bonds of the W-C type, adding considerable stability to the double helix.

Chemische Eigenschaften

White Powder

Verwenden

2-Aminoadenosine is a nucleoside analog as inhibitor or substrate of adenosine kinase from M. tuberculosis. It is also used to synthesize 2′-O-methyl and 3′-O-methyl Guanosine.

Definition

ChEBI: 2-Aminoadenosine is a purine nucleoside.

Synthese

The synthesis of 2-aminoadenosine (2-AA): Assays were performed in 5 and 10% of aprotic dipolar co-solvents, at 60°C, twelve units/ml cell lysate were added to 150 ml of a solution kept thermostatically at 60 °C, and having the following composition of substrate solutions: 15mM Uridine/2 ' -Deoxyuridine,5 mM 2,6-Diaminopurine, and 30 mM potassium phosphate buffer, pH 7. After 5 hours, the reaction mixture was filtered by centrifugation at 2000 x g for 30 min, at 4°C, through an Amicon ultra-4 Centrifugal Filter Devices (Millipore, Bedford, MA) with a 3000-Da cutoff, and the filtrate was recovered. synthesis of 2-aminoadenosine

Einzelnachweise

Pyrazolo[3,4-d]pyrimidine ribonucleosides related to 2-aminoadenosine and isoguanosine: synthesis, deamination and tautomerism. DOI: 10.1039/B708736E
An Efficient Process for Synthesis of 2′-O-methyl and 3′-O-methyl Guanosine from 2-aminoadenosine Using Diazomethane and the Catalyst Stannous Chloride. DOI: 10.1080/15257770500544529

2-Aminoadenosine Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


2-Aminoadenosine Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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2096-10-8()Verwandte Suche:


  • 2-AMINOADENOSINE
  • 2-AMINOADENOSINE HPLC98+%
  • (2R,3R,4S,5R)-2-(2,6-Diaminopurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol
  • 2-AMinoadenosin
  • 2-NH2-Ar
  • 2-Aminoadenosine≥ 99% (HPLC)
  • 2,6-DiaMino-9-β-D-ribofuranosyl-9H-purine
  • 2,6-DiaMinonebularine
  • 2,6-DiaMinopurinosine
  • 9-β-Ribosyl-2,6-diaMinopurine
  • NSC 7363
  • 2,6-Diamino-9-(beta-D-ribofuranosyl)purine 2,6-Diaminopurine Riboside
  • Adenosine, 2-amino-
  • Regadenoson Impurity 23
  • 2, 6-Diaminopurine-riboside / 2-amino-adenosine
  • 9H-Purine-2,6-diamine, 9-.β.-D-ribofuranosyl-
  • 2-aminoadenine nucleoside
  • 2-Aminoadenosine >
  • 2,6-Diamino-9-(beta-D-ribofuranosyl)purine
  • 2-Aminoadenosine USP/EP/BP
  • TIANFU CHEM 2-Aminoadenosine
  • 2-AMINE ADENOSINE
  • 2,6-DIAMINOPURINE RIBOSIDE
  • Aminoadenosine
  • 2-NH2-A
  • 2-NH2-rA
  • 0/8/96
  • (2R,3R,4S,5R)-2-(2,6-Diamino-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol
  • 2-NH?-rA
  • Regadenoson Impurity U18
  • 2096-10-8
  • 96-10-8
  • 2090-10-8
  • C10H14N6O4
  • Amines
  • Heterocycles
  • Nucleotides and Nucleosides
  • Nucleic acids
  • Bases & Related Reagents
  • Nucleotides
  • 2096-10-8
  • Nucleosides-Ribonucleosides
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