Fluorinated VHL Spy Molecule 2

2290526-27-9

CAS-Nr.: 2290526-27-9

Englisch Name:: Fluorinated VHL Spy Molecule 2

Synonyma:: Fluorinated VHL Spy Molecule 2;2-Pyrrolidinecarboxamide, N-[(4-bromophenyl)methyl]-4-hydroxy-1-(2,2,2-trifluoroacetyl)-, (2S,4R)-;(2S,4R)-N-(4-bromobenzyl)-4-hydroxy-1-(2,2,2-trifluoroacetyl)pyrrolidine-2-carboxamide, VHL reporter ligand

CBNumber:: CB25541856

Summenformel:: C14H14BrF3N2O3

Molgewicht:: 395.17

MOL-Datei:: 2290526-27-9.mol

Request For Quotation

Eigenschaften Sicherheit Verwendungswort Produktionsfirma 6

Fluorinated VHL Spy Molecule 2 Eigenschaften

Siedepunkt:: 624.2±55.0 °C(Predicted)

Dichte: 1.637±0.06 g/cm3(Predicted)

pka: 13.62±0.40(Predicted)

Sicherheit

Fluorinated VHL Spy Molecule 2 Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Fluorinated VHL Spy Molecule 2 can be used for the discovery of new von Hippel-Lindau (VHL) binders. Based on VH032 (cat# 901490), this reporter was designed in the lab of Alessio Ciulli to bind the hydroxyproline (Hyp) recognition site of VHL. When used in competition ligand-observed 19F NMR screening experiments, its displacement indicates binding by another molecule. Additional Fluorinated VHL Spy Molecules are available as listings 909459, 909440, and 909416.
The E3 ligase VHL is of growing interest for targeted protein degradation and these spy molecules will facilitate the identification of novel VHL ligands and VHL-based degraders.

Fluorinated VHL Spy Molecule 2 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

Fluorinated VHL Spy Molecule 2 Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 6)Lieferanten

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
Aladdin Scientific	+1-+1(833)-552-7181	sales@aladdinsci.com	United States	52927	58
Sigma-Aldrich	021-61415566 800-8193336	orderCN@merckgroup.com	China	51471	80
Shanghai Chaolan Chemical Technology Center	QQ:65489617 15618227136	info@SuperLan-chem.com	China	9874	58
Jilin Province Woda Biotechnology Co., Ltd.	13504435624	1927928688@qq.com	China	1367	58
Changzhou Bojia Biomedical Technology Co., Ltd.	2122619822	czbjpharma@126.com	China	18488	58
Shanghai Aladdin Biochemical Technology Co.,Ltd.	+86-18521732826	market@aladdin-e.com	China	48467	58

Fluorinated VHL Spy Molecule 2
2-Pyrrolidinecarboxamide, N-[(4-bromophenyl)methyl]-4-hydroxy-1-(2,2,2-trifluoroacetyl)-, (2S,4R)-
(2S,4R)-N-(4-bromobenzyl)-4-hydroxy-1-(2,2,2-trifluoroacetyl)pyrrolidine-2-carboxamide, VHL reporter ligand
2290526-27-9