Carbamic acid, N-?[(2,?4-?difluorophenyl)?methyl]?-?, (3R)?-?3-?[7-?[[[(2,?4-?difluorophenyl)?methyl]?amino]?carbonyl]?-?1,?8-?dihydro-?9-?hydroxy-?1,?8-?dioxo-?2H-?pyrido[1,?2-?a]?pyrazin-?2-?yl]?butyl ester

2244161-73-5

CAS-Nr.: 2244161-73-5

Englisch Name:: Carbamic acid, N-?[(2,?4-?difluorophenyl)?methyl]?-?, (3R)?-?3-?[7-?[[[(2,?4-?difluorophenyl)?methyl]?amino]?carbonyl]?-?1,?8-?dihydro-?9-?hydroxy-?1,?8-?dioxo-?2H-?pyrido[1,?2-?a]?pyrazin-?2-?yl]?butyl ester

Synonyma:: DOLUTEGRAVIR IMPURITY;Dolutegravir Impurity 60;sodium (R)-7-((2,4-difluorobenzyl)carbamoyl)-2-(4-(((2,4-difluorobenzyl)carbamoyl)oxy)butan-2-yl)-1,

CBNumber:: CB28214977

Summenformel:: C28H24F4N4O6

Molgewicht:: 588.51

MOL-Datei:: 2244161-73-5.mol

Request For Quotation

Eigenschaften Sicherheit Verwendungswort Produktionsfirma 10

Carbamic acid, N-?[(2,?4-?difluorophenyl)?methyl]?-?, (3R)?-?3-?[7-?[[[(2,?4-?difluorophenyl)?methyl]?amino]?carbonyl]?-?1,?8-?dihydro-?9-?hydroxy-?1,?8-?dioxo-?2H-?pyrido[1,?2-?a]?pyrazin-?2-?yl]?butyl ester Eigenschaften

Siedepunkt:: 778.0±60.0 °C(Predicted)

Dichte: 1.51±0.1 g/cm3(Predicted)

pka: 4.50±1.00(Predicted)

Sicherheit

Carbamic acid, N-?[(2,?4-?difluorophenyl)?methyl]?-?, (3R)?-?3-?[7-?[[[(2,?4-?difluorophenyl)?methyl]?amino]?carbonyl]?-?1,?8-?dihydro-?9-?hydroxy-?1,?8-?dioxo-?2H-?pyrido[1,?2-?a]?pyrazin-?2-?yl]?butyl ester Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Des-butanoyl 3,4-Didehydro-N-butyl(2,4-difluorobenzyl)carbamate Dolutegravir is an impurity of Dolutegravir (D528800), a second generation HIV-1 integrase strand transfer inhibitor. Dolutegravir is currently in Phase III clinical trials for the treatment of HIV infection. Dolutegravir has been shown to potently inhibit HIV replication in cells such as peripheral blood mononuclear cells (PBMCs), MT-4 cells and CIP4 cells infected with a self-inactivating PHIV lentiviral vector.

Carbamic acid, N-?[(2,?4-?difluorophenyl)?methyl]?-?, (3R)?-?3-?[7-?[[[(2,?4-?difluorophenyl)?methyl]?amino]?carbonyl]?-?1,?8-?dihydro-?9-?hydroxy-?1,?8-?dioxo-?2H-?pyrido[1,?2-?a]?pyrazin-?2-?yl]?butyl ester Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

Carbamic acid, N-?[(2,?4-?difluorophenyl)?methyl]?-?, (3R)?-?3-?[7-?[[[(2,?4-?difluorophenyl)?methyl]?amino]?carbonyl]?-?1,?8-?dihydro-?9-?hydroxy-?1,?8-?dioxo-?2H-?pyrido[1,?2-?a]?pyrazin-?2-?yl]?butyl ester Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 10)Lieferanten

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
AFINE CHEMICALS LIMITED	+86-0571-85134551	sales@afinechem.com	China	15373	58
CR Corporation Limited	+8613062833949	fred.wen@crcorporation.cn	China	8647	58
China National Standard Pharmaceutical Corporation Limited	+8615391658522	overseasales@yongstandards.com	China	11927	58
Guangzhou Jiuzhi Pharmaceutical Technology Co., Ltd.	020-89854820	sales@jzpharma.cn	China	1081	58
SHENZHEN PHYSTANDARD BIO-TECH CO.,LTD	0755-0755-0755-83725350 13380397412	3001280422@qq.com	China	10044	58
QUALITY CONTROL SOLUTIONS LTD.	0755-66853366; 13670046396	ORDERS@QCSRM.COM	China	18899	58
Shenzhen Roark Pharma-Tec Co., Ltd.	13128912434	2880126944@qq.com	China	2578	58
Aurisco Pharmaceutical (Tianjin) Inc.	022-59885855	liuyujie@aurisco.com	China	96	58
Hubei De'ao Chemical Research Pharmaceutical Technology Co., Ltd	18502726233; 18502726233	3641133981@qq.com	China	9809	58

DOLUTEGRAVIR IMPURITY
sodium (R)-7-((2,4-difluorobenzyl)carbamoyl)-2-(4-(((2,4-difluorobenzyl)carbamoyl)oxy)butan-2-yl)-1,
Dolutegravir Impurity 60
2244161-73-5
C28H24F4N4O6