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Adenanthin

111917-59-0

CAS-Nr.: 111917-59-0

Englisch Name:: Adenanthin

Synonyma:: Adenanthin;Actinodephnine Acuminatin Acuminatoside Adenanthin;Kaur-16-ene-6,15-dione, 1,7,11-tris(acetyloxy)-3-hydroxy-, (1α,3β,7β,11β)-;Kaur-16-ene-6,15-dione,1,7,11-tris(acetyloxy)-3-hydroxy-, (1a,3b,7b,11b)- (9CI)

CBNumber:: CB31267733

Summenformel:: C26H34O9

Molgewicht:: 490.55

MOL-Datei:: 111917-59-0.mol

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Eigenschaften Sicherheit Verwendungswort Produktionsfirma 60

Adenanthin Eigenschaften

Siedepunkt:: 593.4±50.0 °C(Predicted)

Dichte: 1.29±0.1 g/cm3(Predicted)

pka: 14.13±0.70(Predicted)

Sicherheit

Adenanthin Chemische Eigenschaften,Einsatz,Produktion Methoden

Enzyminhibitor

This diterpenoid (FW = 484.63 g/mol; CAS 111917-59-0) from the leaves of Rabdosia adenantha, induces differentiation of acute promyelocytic leukemia (APL) cells. Adenanthin targets the conserved cysteine thiols of peroxiredoxins I and II (or Prx I and Prx II), inhibiting their peroxidase activities and consequently increasing cellular hydrogen peroxide. The latter leads to the activation of Extracellular signal-Regulated Kinases (ERKs) and increased transcription of CCAAT/enhancer-binding protein β (or C/EBPs), further contributing to differentiation. Adenanthin induces APL-like cell differentiation, represses tumor growth in vivo and prolongs the survival of mouse APL models that are sensitive and resistant to retinoic acid.

Adenanthin Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

Adenanthin Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 60)Lieferanten

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
Hubei Jusheng Technology Co.,Ltd.	18871490254	linda@hubeijusheng.com	CHINA	28180	58
Shaanxi Pioneer Biotech Co., Ltd .	+8613259417953	sales@pioneerbiotech.com	China	3000	58
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19553	58
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	19892	58
Aktin Chemicals, Inc.	028-85159085	info@aktinchem.com	CHINA	1025	58
Labnetwork lnc.	+86-27-50766799 +8618062016861	contact@labnetwork.com	China	19994	58
Shanghai Acmec Biochemical Technology Co., Ltd.	+undefined18621343501	product@acmec-e.com	China	33350	58
Chembest Research Laboratories Limited	021-20908456	sales@BioChemBest.com	China	6008	61
BioBioPha Co., Ltd.	0871-65217109 13211707573;	y.liu@mail.biobiopha.com	China	5654	65
Sichuan Wei Keqi Biological Technology Co., Ltd.	028-81700200 18116577057	3003855609@qq.com	China	7892	56

111917-59-0()Verwandte Suche:

p-Menth-1-en-8-ol Stigmast-5-en-3-β-ol Gonadotropin, Pregnant Mare Serum Gonadotropin, chorionisch

Adenanthin
Actinodephnine Acuminatin Acuminatoside Adenanthin
Kaur-16-ene-6,15-dione,1,7,11-tris(acetyloxy)-3-hydroxy-, (1a,3b,7b,11b)- (9CI)
Kaur-16-ene-6,15-dione, 1,7,11-tris(acetyloxy)-3-hydroxy-, (1α,3β,7β,11β)-
111917-59-0