fialuridine monophosphate

fialuridine monophosphate Struktur
99891-31-3
CAS-Nr.
99891-31-3
Englisch Name:
fialuridine monophosphate
Synonyma:
fialuridine monophosphate;Fialuridine 5'-Monophosphate;1-(2-Deoxy-2-fluoro-5-O-phosphono-β-D-arabinofuranosyl)-5-iodo-2,4(1H,3H)-pyriMidinedione;2,4(1H,3H)-Pyrimidinedione, 1-(2-deoxy-2-fluoro-5-O-phosphono-β-D-arabinofuranosyl)-5-iodo-;[(2R,3R,4S,5R)-4-fluoro-3-hydroxy-5-(5-iodo-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methyl dihydrogen phosphate
CBNumber:
CB31390358
Summenformel:
C9H11FIN2O8P
Molgewicht:
452.0688742
MOL-Datei:
99891-31-3.mol

fialuridine monophosphate Eigenschaften

Dichte
2.26±0.1 g/cm3(Predicted)
pka
1.86±0.10(Predicted)

Sicherheit

fialuridine monophosphate Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Fialuridine 5’-Monophosphate (FIAUMP) is the phosphorylated derivative and major metabolite of the antiviral agent Fialuridine (F335000). Studies show that purified mammalian DNA polymerases were able to incorporate FIAUMP into the nascent DNA chain during in vitro DNA synthesis.

fialuridine monophosphate Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


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  • 1-(2-Deoxy-2-fluoro-5-O-phosphono-β-D-arabinofuranosyl)-5-iodo-2,4(1H,3H)-pyriMidinedione
  • fialuridine monophosphate
  • Fialuridine 5'-Monophosphate
  • [(2R,3R,4S,5R)-4-fluoro-3-hydroxy-5-(5-iodo-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methyl dihydrogen phosphate
  • 2,4(1H,3H)-Pyrimidinedione, 1-(2-deoxy-2-fluoro-5-O-phosphono-β-D-arabinofuranosyl)-5-iodo-
  • 99891-31-3
  • C9H11FIN2O8P
  • Bases & Related Reagents
  • Intermediates & Fine Chemicals
  • Metabolites & Impurities
  • Nucleotides
  • Pharmaceuticals
  • Phosphorylating and Phosphitylating Agents
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