Sevelamer carbonate
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- CAS-Nr.
- 845273-93-0
- Englisch Name:
- Sevelamer carbonate
- Synonyma:
- Sevelam;Sevelam carbonate;Sevelamer carbonate;SEVELEMER CARBONATE;2-Propen-1-aminepolymerwith;Sevelamer Carbonate, Technical Grade;SIM862 Sevelamer Carbonate-----25gm;2-Propen-1-amine polymer with (chloromethyl)oxiran;carbonic acid,2-(chloromethyl)oxirane,prop-2-en-1-amine;2-Propen-1-amine polymer with (chloromethyl)oxirane carbonate
- CBNumber:
- CB32128754
- Summenformel:
- C7H14ClNO4
- Molgewicht:
- 211.64
- MOL-Datei:
- 845273-93-0.mol
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Sevelamer carbonate Eigenschaften
- storage temp.
- Room Temperature, under inert atmosphere
- Löslichkeit
- <4.74mg/mL in DMSO
- Aggregatzustand
- Solid
- Farbe
- White to Pale Beige
- InChI
- InChI=1S/C3H5ClO.C3H7N.CH2O3/c4-1-3-2-5-3;1-2-3-4;2-1(3)4/h3H,1-2H2;2H,1,3-4H2;(H2,2,3,4)
- InChIKey
- PADGNZFOVSZIKZ-UHFFFAOYSA-N
- SMILES
- C(O)(O)=O.C(C1OC1)Cl.C(=C)CN
Sicherheit
- Risiko- und Sicherheitserklärung
- Gefahreninformationscode (GHS)
| Bildanzeige (GHS) |
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| Alarmwort |
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| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H412 |
Schädlich für Wasserorganismen, mit langfristiger Wirkung. |
Langfristig (chronisch) gewässergefährdend |
Kategorie 3 |
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P273, P501 |
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| Sicherheit |
| P273 |
Freisetzung in die Umwelt vermeiden. |
| P501 |
Inhalt/Behälter ... (Entsorgungsvorschriften vom Hersteller anzugeben) zuführen. |
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Sevelamer carbonate Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
Sevelamer carbonate (SC) is a non-absorbed phosphate binding crosslinked polymer, with the same polymeric structure as sevelamer hydrochloride, in which carbonate replaces chloride as the counterion. SC has been found to have the same safety and efficacy profile as Sevelamer HCl in HD patients.
Sevelamer carbonate(Renvela) is a nonaluminum, non-calcium-basedphosphorus binder that traps phosphorus in the bowel through ion exchange and hydrogen binding. This drug replaced sevelamer hydrochloride(Renagel) and has an advantage of not generating an acid load, as its precursor, sevelamer hydrochloride, did. It also has the advantage of lowering LDL cholesterol due to gut binding of bile acids.
Verwenden
Sevelamer Carbonate, a non-?absorbed polymer is an oral phosphate binder in patients with kidney failure. It is reported that Sevelamer Carbonate is less likely to cause hypercalcemia, low levels of PTH, and progressive coronary and aortic calcification in hemodialysis patients than calcium-?based phosphate binders.
Mode of action
The active substance in Sevelamer carbonate Winthrop, sevelamer carbonate, is a phosphate binder. When taken with meals, it attaches in the gut to phosphate from the food, thereby preventing the phosphate from being absorbed into the body and helping to reduce phosphate levels in the blood.
Sevelamer carbonate Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Sevelamer carbonate Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
Global( 206)Lieferanten
845273-93-0()Verwandte Suche:
- 2-Propen-1-amine polymer with (chloromethyl)oxirane carbonate
- Sevelamer carbonate
- Carbonic acid, compd. with 2-(chloromethyl)oxirane polymer with 2-propen-1-amine
- Sevelam
- 2-Propen-1-amine polymer with (chloromethyl)oxiran
- 2-Propen-1-aminepolymerwith
- carbonic acid,2-(chloromethyl)oxirane,prop-2-en-1-amine
- SIM862 Sevelamer Carbonate-----25gm
- Sevelamer Carbonate, Technical Grade
- 2-Propen-1-amine polymer with (chloromethyl)oxirane carbonate ISO 9001：2015 REACH
- Sevelam carbonate
- SEVELEMER CARBONATE
- 845273-93-0
- C3H7NmC3H5ClOnCH2O3x
- C3H7NC3H5ClOxxCH2O3
- Inhibitors
- Pharmaceutical intermediate
- Other APIs
