(±)17-HETE Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
Electrolyte and fluid transport in the kidney are regulated in part by arachidonic acid and its metabolites. (±)17-
HETE is the racemic version of a cytochrome P450 (CYP450) metabolite of arachidonic acid that has stereospecific effects on sodium transport in the kidney. At a concentration of 2 μM the (S)-
enantiomer of 17-
HETE inhibits proximal tubule ATPase activity by as much as 70%, whereas the (R)-
isomer is inactive.
Definition
ChEBI: A HETE that consists of arachidonic acid bearing an additional hydroxy substituent at position 17.
(±)17-HETE Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
