3-(3-(Trifluoromethyl)phenyl)propanal
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- CAS-Nr.
- 21172-41-8
- Englisch Name:
- 3-(3-(Trifluoromethyl)phenyl)propanal
- Synonyma:
- 3-(3-(trifluoroMethyl)phenyl)propanal;Cinacalcet Impurity 54;3-(Trifluoromethyl)benzenepropanal;4-[3-(trifluoroMethyl)phenyl]butanal;Benzenepropanal, 3-(trifluoroMethyl)-;m-(Trifluoromethyl)hydrocinnamaldehyde;3-(trifluoroMethylphenyl)propionaldehyde;3-(3-TRIFLUOROMETHYL-PHENYL)-PROPIOLDEHYDE;3-(3-TRIFLUOROMETHYL-PHENYL)-PROPIONALDEHYDE
- CBNumber:
- CB3420003
- Summenformel:
- C10H9F3O
- Molgewicht:
- 202.17
- MOL-Datei:
- 21172-41-8.mol
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3-(3-(Trifluoromethyl)phenyl)propanal Eigenschaften
- Siedepunkt:
- 207.4±35.0 °C(Predicted)
- Dichte
- 1.192±0.06 g/cm3(Predicted)
- storage temp.
- Inert atmosphere,Store in freezer, under -20°C
- Löslichkeit
- Soluble in Chloroform, Dichloromethane, Ethyl acetate
- Aggregatzustand
- Oil
- Farbe
- Clear colorless to pale yellow oily liquid
- Stabilität:
- Not very stable, new spot on TLC if kept at r.t. o/n.
- InChI
- InChI=1S/C10H9F3O/c11-10(12,13)9-5-1-3-8(7-9)4-2-6-14/h1,3,5-7H,2,4H2
- InChIKey
- APCCHYPQHODSBD-UHFFFAOYSA-N
- SMILES
- C1(CCC=O)=CC=CC(C(F)(F)F)=C1
3-(3-(Trifluoromethyl)phenyl)propanal Chemische Eigenschaften,Einsatz,Produktion Methoden
Chemische Eigenschaften
Colourless Oil
Verwenden
3-(Trifluoromethyl)benzenepropanal (cas# 21172-41-8) is a compound useful in organic synthesis.
Synthese
A solution of 3-(Trifluoromethyl) benzene propanol (1.0 g, 4.90 mmol) in dichloromethane (20 ml) is cooled in a water/ice bath, treated in succession with DMSO (770 mg, 9.80 mmol) and P2O5 (1.39 g, 9.80 mmol) and left under stirring for 30 minutes, while temperature raises to 20°C. The reaction mixture is then cooled in water/ice bath and triethylamine (2.4 ml, 17.15 mmol). The resulting solution is kept under stirring while the temperature raises to 20°C. After one hour, the mixture is treated with 5 per cent HCl, the phases are separated, and the organic one is further washed with 5 per cent HCl. The organic phase is then washed with brine, dried over Na2SO4, filtered and concentrated under reduced pressure to afford 0.99 g of the aldehyde of 3-(3-(Trifluoromethyl)phenyl)propanal in quantitative yield.
3-(3-(Trifluoromethyl)phenyl)propanal Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
3-(3-(Trifluoromethyl)phenyl)propanal Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
Global( 175)Lieferanten
21172-41-8()Verwandte Suche:
- 3-(3-TRIFLUOROMETHYL-PHENYL)-PROPIONALDEHYDE
- 3-(Trifluoromethyl)benzenepropanal
- m-(Trifluoromethyl)hydrocinnamaldehyde
- 4-[3-(trifluoroMethyl)phenyl]butanal
- Benzenepropanal, 3-(trifluoroMethyl)-
- 3-(trifluoroMethylphenyl)propionaldehyde
- 3-(3-TRIFLUOROMETHYL-PHENYL)-PROPIOLDEHYDE
- Cinacalcet Impurity 54
- 3-(3-(trifluoroMethyl)phenyl)propanal
- 21172-41-8
- Cinacalcet Intermediate
- Aromatics Compounds
- Aromatics
