FHD-286

2671128-05-3

CAS-Nr.: 2671128-05-3

Englisch Name:: FHD-286

Synonyma:: FHD-286;Inhibitor,inhibit,FHD 286,FHD-286,Epigenetic Reader Domain,FHD286;N-[(S)-1-[[4-[6-[(2R,6S)-2,6-Dimethylmorpholino]-2-pyridyl]-2-thiazolyl]amino]-3-methoxy-1-oxo-2-propyl]-1-(methylsulfonyl)-1H-pyrrole-3-carboxamide;N-[(1S)-2-[[4-[6-[cis-2,6-dimethylmorpholin-4-yl]-2-pyridyl]thiazol-2-yl]amino]-1-(methoxymethyl)-2-oxo-ethyl]-1-methylsulfonyl-pyrrole-3-carboxamide;N-[(2S)-1-[[4-[6-[(2S,6R)-2,6-dimethyl-4-morpholinyl]-2-pyridinyl]-2-thiazolyl]amino]-3-methoxy-1-oxopropan-2-yl]-1-methylsulfonyl-3-pyrrolecarboxamide;1H-Pyrrole-3-carboxamide, N-[(1S)-2-[[4-[6-[(2R,6S)-2,6-dimethyl-4-morpholinyl]-2-pyridinyl]-2-thiazolyl]amino]-1-(methoxymethyl)-2-oxoethyl]-1-(methylsulfonyl)-

CBNumber:: CB410298404

Summenformel:: C24H30N6O6S2

Molgewicht:: 562.66

MOL-Datei:: 2671128-05-3.mol

Request For Quotation

Eigenschaften Sicherheit Verwendungswort Produktionsfirma 44

FHD-286 Eigenschaften

Dichte: 1.46±0.1 g/cm3(Predicted)

storage temp.: Store at -20°C

Löslichkeit: DMSO : 250 mg/mL (444.32 mM; Need ultrasonic)

Aggregatzustand: Solid

pka: 7.18±0.50(Predicted)

Farbe: Off-white to light yellow

InChIKey: JBLQNFBXKOAIHG-FCEWJHQRSA-N

SMILES: N1(S(C)(=O)=O)C=CC(C(N[C@@H](COC)C(NC2=NC(C3=NC(N4C[C@H](C)O[C@H](C)C4)=CC=C3)=CS2)=O)=O)=C1

Sicherheit

FHD-286 Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

FHD-286 is a highly potent, selective, allosteric and orally available, small-molecule, enzymatic inhibitor of BRG1 (SMARCA4) and BRM (SMARCA2), two highly similar proteins that are the ATPases, or the catalytic engines of the BAF complex, one of the critical regulators within the chromatin regulatory system. In preclinical studies, FHD-286 has shown anti-tumour activity across a broad range of malignancies, including hematologic and solid tumours. FHD-286 is being developed for relapsed and/or refractory AML.

FHD-286 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

FHD-286 Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 44)Lieferanten

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
Nantong HI-FUTURE Biology Co., Ltd.	+undefined18051384581	sales@chemhifuture.com	China	3136	58
Aladdin Scientific	+1-+1(833)-552-7181	sales@aladdinsci.com	United States	52927	58
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32760	60
TargetMol Chemicals Inc.	+1-781-999-5354	support@targetmol.com	United States	19973	58
Zepeptide Biotechnology (Shijiazhuang) Co., Ltd	+86-86-13383293380 +8613230482270	1919301810@qq.com	China	141	58
Nanjing Bicbiotechnology Co., Ltd	+86-2552131256 +86-18251840740	sales@bicbiotech.com	China	6000	58
Wuhan Jingkang en Biomedical Technology Co., Ltd	+8613720134139	orders@jknbiochem.com	China	4694	58
Shanghai XingMo Biotechnology Co., Ltd.	13524779951	2075692521@qq.com	China	310	55
WUHAN SUN-SHINE BIO-TECHNOLOGY Co., Ltd.	17702719238 17702719238	sales@sun-shinechem.com	China	950	64
ShangHai Caerulum Pharma Discovery Co., Ltd.	18149758185	sales-cpd@caerulumpharma.com	China	3465	58

1H-Pyrrole-3-carboxamide, N-[(1S)-2-[[4-[6-[(2R,6S)-2,6-dimethyl-4-morpholinyl]-2-pyridinyl]-2-thiazolyl]amino]-1-(methoxymethyl)-2-oxoethyl]-1-(methylsulfonyl)-
FHD-286
Inhibitor,inhibit,FHD 286,FHD-286,Epigenetic Reader Domain,FHD286
N-[(1S)-2-[[4-[6-[cis-2,6-dimethylmorpholin-4-yl]-2-pyridyl]thiazol-2-yl]amino]-1-(methoxymethyl)-2-oxo-ethyl]-1-methylsulfonyl-pyrrole-3-carboxamide
N-[(S)-1-[[4-[6-[(2R,6S)-2,6-Dimethylmorpholino]-2-pyridyl]-2-thiazolyl]amino]-3-methoxy-1-oxo-2-propyl]-1-(methylsulfonyl)-1H-pyrrole-3-carboxamide
N-[(2S)-1-[[4-[6-[(2S,6R)-2,6-dimethyl-4-morpholinyl]-2-pyridinyl]-2-thiazolyl]amino]-3-methoxy-1-oxopropan-2-yl]-1-methylsulfonyl-3-pyrrolecarboxamide
2671128-05-3
671128-05-3
C24H30N6O6S2