AMBENONIUM Chemische Eigenschaften,Einsatz,Produktion Methoden
Definition
ChEBI: A symmetrical oxalamide-based bis-quaternary ammonium ion having ethyl and 2-chlorobenzyl groups attached to the nitrogens.
Trademarks
Mytelase (Sanofi Aventis).
Pharmakologie
The pharmacological properties of ambenonium are similar to neostigmine and pyridostigmine, and it works by reversible inactivation of cholinesterase.
Synthese
Ambenonium, [oxalyl-bis-(iminoethylen)]-bis-[ortho-(chlorobenzyl)
diethylammonium] chloride (13.2.15), is made by reacting diethyloxalate with two moles of
N,N-diethylethylendiamine, forming oxalyl-bis-(iminoethylen)-bis-N,N-diethylamine
(13.2.14), which is alkylated by two moles of 2-chlorobenzylchloride, giving ambenonium
(13.2.15) [46¨C48].
AMBENONIUM Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
