5-PREGNEN-3BETA-OL-20-ONE-16ALPHA-CARBONITRILE

5-PREGNEN-3BETA-OL-20-ONE-16ALPHA-CARBONITRILE Struktur
1434-54-4
CAS-Nr.
1434-54-4
Englisch Name:
5-PREGNEN-3BETA-OL-20-ONE-16ALPHA-CARBONITRILE
Synonyma:
pcn;sc4674;U-14975;16-alpha-cyanopregnenolone;pregnenolone-16α-carbonitrile;Pregnenolone 16α-carbonitrile;5-PREGNEN-16α-CYANO-3β-OL-20-ONE;PREGNENOLONE-16ALPHA-CARBONITRILE;16α-Cyano-3β-hydroxypregn-5-en-20-one;5-pregnen-3B-ol-20-one-16A-carbonitrile
CBNumber:
CB4150567
Summenformel:
C22H31NO2
Molgewicht:
341.49
MOL-Datei:
1434-54-4.mol

5-PREGNEN-3BETA-OL-20-ONE-16ALPHA-CARBONITRILE Eigenschaften

Schmelzpunkt:
225-228 °C(Solv: methanol (67-56-1); benzene (71-43-2))
Siedepunkt:
508.5±50.0 °C(Predicted)
Dichte
1.13±0.1 g/cm3(Predicted)
Flammpunkt:
93 °C
storage temp. 
2-8°C
Löslichkeit
Acetonitrile: 1 mg/ml; Ethanol: 1 mg/ml; Methanol: 1 mg/ml
Aggregatzustand
White to off-white solid.
pka
14.95±0.70(Predicted)
Farbe
White to off-white
EPA chemische Informationen
Pregn-5-ene-16-carbonitrile, 3-hydroxy-20-oxo-, (3.beta.,16.alpha.)- (1434-54-4)

Sicherheit

WGK Germany  3
RTECS-Nr. TU4536500

5-PREGNEN-3BETA-OL-20-ONE-16ALPHA-CARBONITRILE Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Pregnenolone Carbonitrile is a glucocorticoid receptor antagonist that induces the expression of the CYP3A family of steroid hydroxylases and modulates sterol and bile acid biosynthesis in vivo. Pregnenolone Carbonitrile is an an activator of rat pregnane X receptor (PXR).

Biochem/physiol Actions

Pregnenolone-16a-carbonitrile (PCN) is a glucocorticoid receptor antagonist and a PXR (pregnane X receptor) activator.

5-PREGNEN-3BETA-OL-20-ONE-16ALPHA-CARBONITRILE Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


5-PREGNEN-3BETA-OL-20-ONE-16ALPHA-CARBONITRILE Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 35)Lieferanten
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1434-54-4()Verwandte Suche:


  • 5-PREGNEN-3BETA-OL-20-ONE-16ALPHA-CARBONITRILE
  • 5-pregnen-3B-ol-20-one-16A-carbonitrile
  • (3S,8S,9S,10R,13S,14S,16R,17S)-17-acetyl-3-hydroxy-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-16-carbonitrile
  • (3S,8S,9S,10R,13S,14S,16R,17S)-17-ethanoyl-3-hydroxy-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-16-carbonitrile
  • pregnenolone-16α-carbonitrile
  • 16α-Cyano-3β-hydroxypregn-5-en-20-one
  • U-14975
  • 16-alpha)-3-hydroxy-20-oxopregn-5-ene-16-carbonitrile(3-bet
  • 16-alpha-cyanopregnenolone
  • 3beta-hydroxy-20-oxo-pregn-5-ene-16-alpha-carbonitril
  • 3-hydroxy-20-oxo-,(3-beta,16-alpha)-pregn-5-ene-16-carbonitril
  • pcn
  • sc4674
  • PREGNENOLONE-16ALPHA-CARBONITRILE
  • Pregn-5-ene-16-carbonitrile, 3-hydroxy-20-oxo-, (3β,16α)-
  • CYPs,Cytochrome P450,P4503A,orally,Pregnenolone Carbonitrile,Pregnenolone 16α-carbonitrile,Inhibitor,PXR,cytochrome,inhibit
  • 5-PREGNEN-16α-CYANO-3β-OL-20-ONE
  • Pregnenolone 16α-carbonitrile
  • 1434-54-4
  • C22H31NO2
  • BioChemical
  • Cell Signaling and Neuroscience
  • Cell Biology
  • Cytokines, Growth Factors and Hormones
  • Corticosterone
  • Hormones
  • Steroid Hormones
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