tert-Butyl 6-[(1E)-2-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]ethenyl]-2,2-dimethyl-1,3-dioxane-4-acetate

tert-Butyl 6-[(1E)-2-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]ethenyl]-2,2-dimethyl-1,3-dioxane-4-acetate Struktur
289042-12-2
CAS-Nr.
289042-12-2
Englisch Name:
tert-Butyl 6-[(1E)-2-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]ethenyl]-2,2-dimethyl-1,3-dioxane-4-acetate
Synonyma:
R1 ROSUVASTATIN;(4R,6S)-6-[(1E)-2-[4-(4-FLUOROPHENYL)-6-(1-METHYLETHYL)-2-[METHYL(METHYLSULFONYL)AMINO]-5-PYRIMIDINYL]ETHENYL]-2,2-DIMETHYL-1,3-DIOXANE-4-ACETIC ACID, 1,1-DIMETHYLETHYL ESTER;Rosuvastatin R1;tert-Butyl 2-((4R,6S)-6-((E)-2-(4-(4-fluorophenyl)-6-isopropyl-2-(N-MethylMethylsulfonaMido)pyriMidin-5-yl)vinyl)-2,2-diMethyl-1,3-dioxan-4-yl)acetate;6-[(1E)-2-[4-(4-Fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]ethenyl]-2,2-dimethyl-1,3-dioxane-4-acetic acid 1,1-dimethylethyl ester;Rosuvastatin intermediate R-2;tert-Butyl 6-[(1E)-2-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]ethenyl]-2,2-dimethyl-1,3-dioxane-4-acetat;R-1 interMediate;Rosuvastatin BEM;RSV Intermediate
CBNumber:
CB4200581
Summenformel:
C29H40FN3O6S
Molgewicht:
577.71
MOL-Datei:
289042-12-2.mol

tert-Butyl 6-[(1E)-2-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]ethenyl]-2,2-dimethyl-1,3-dioxane-4-acetate Eigenschaften

Schmelzpunkt:
153-155°C
Siedepunkt:
673.3±65.0 °C(Predicted)
Dichte
1.210
storage temp. 
Inert atmosphere,2-8°C
Löslichkeit
Chloroform (Slightly), Methanol (Slightly)
Aggregatzustand
Solid
pka
-0.43±0.10(Predicted)
Farbe
White to Off-White
CAS Datenbank
289042-12-2(CAS DataBase Reference)

Sicherheit

HS Code  2935909550

tert-Butyl 6-[(1E)-2-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]ethenyl]-2,2-dimethyl-1,3-dioxane-4-acetate Chemische Eigenschaften,Einsatz,Produktion Methoden

Chemische Eigenschaften

White Solid

tert-Butyl 6-[(1E)-2-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]ethenyl]-2,2-dimethyl-1,3-dioxane-4-acetate Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


tert-Butyl 6-[(1E)-2-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]ethenyl]-2,2-dimethyl-1,3-dioxane-4-acetate Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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289042-12-2()Verwandte Suche:


  • tert-Butyl 6-[(1E)-2-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]ethenyl]-2,2-dimethyl-1,3-dioxane-4-acetate
  • Tert-Butyl-(+)7-[4-(4-Fluorophenyl)-6-Isopropyl-2-(N-Methyl-N-Methyl Sulfonylamino)Pyrimidine-5-Yl]-(3r,5s)-Dioxane-(E)-6-Heptena
  • Tert-butyl-(+)7-[4-(4-fluorophenyl)-6-isopropyl-2-(n-methyl,n-methyl sulphonyl amino) pyrimidine-5-yl]-(3r-5s)-dioxane-(e)-6 heptane
  • Tert-butyl –(+)7-[4-(4-fluorophenyl)-6-lsopropyl -2-(N-methylsulfonylamino)-pyrlmidine-5-yl]-(3R,5S)- dioxane-(E)-6-heptenate
  • Tert-butyl-(+)7-[4-(4-fluorophenyl)-6-isopropyl-2-(N-methyl-N-methylsulfonylamino)pyrimidine-5-yl]-(3R,5S)-dioxane-(E)
  • ERT-BUTYL-(+)7-[4-(4-FLUOROPHENYL)-6-ISOPROPYL-2-(N-METHYL-N-METHYL SULFONYLAMINO)PYRIMIDINE-5-YL] -(3R,5S)-DIOXANE-(E)
  • R-2:Tert-butyl –(+)7-[4-(4-fluorophenyl)-6-lsopropyl -2-(N-methylsulfonylamino)-pyrlmidine-5-yl]-(3R,5S)- dioxane-(E)-6-heptenate
  • (4R,6S)-6-[(1E)-2-[4-(4-Fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]ethenyl]-2,2-dimethyl-1,3-dioxane-4-acetic Acid
  • tert-Butyl 6-[(1E)-2
  • (ZD-8-1) tert-Butyl 6-[(1E)-2-[4-(4-fluorophenyl)-6-(1-Methylethyl)-2-[Methyl(Methylsulfonyl)aMino]-5-pyriMidinyl]ethenyl]-2,2-diMethyl-1,3-dioxane-4-acetate
  • R-1 interMediate
  • 2-{6-[(E)-2-[4-(4-fluorophenyl)-2-(N-MethylMethanesulfonaMido)-6-(propan-2-yl)pyriMidin-5-yl]ethenyl]-2,2-diMethyl-1,3-dioxan-4-yl}-3,3-diMethylbutanoate
  • Rosuvastatin Acetonide t-Butyl Ester
  • Rosuvastatin calciuM interMediate R-2
  • Tert-butyl-(+)7-[4-(4-fluorophenyl)-6-isopropyl-2-( N-METHYL- N-MethylsulfonylaMino)pyriMidine-5-yl]-(3R,5S)-dioxane-(E)-6-heptenate
  • 3-Dioxane-4-acetic acid,6-[(1E)-2-[4-(4-fluorophenyl)-6-(1-Methylethyl)-2-[Methyl(Methylsulfonyl)aMino]-5-pyriMidinyl]ethenyl]-2,2-diMethyl-, 1,1-diMethylethyl ester, (4R,6S)-
  • 1,3-Dioxane-4-acetic acid,6- (1E)-2- 4-(4-fluorophenyl)-6-(1-Methylethyl)-2- Methyl(Methylsulfonyl)aMino -5-pyriMidinyl ethenyl -2,2-diMethyl-, 1,1-diMethylethyl ester, (4R,6S)-
  • Rosuvastatin Acetonide
  • Rosuvastatin EP Impurity F
  • R-1: TERTIARY-BUTYL-(+)-[(4-FLUOROPHENYL)-6-ISOPROPYL-2-(N-METHYL, N-METHYL SULPHONYL AMINO) PYRIMIDINE-5-YL]-(3R-5S)-DIOXANE-(E)-6 HEPTANE
  • 6-[(1E)-2-[4-(4-Fluorophenyl)-6-(1 -methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]ethenyl]-2,2-dimethyl-1,3-dioxane-4-acetic acid 1,1-dimethylethyl ester
  • Rosuvastatin calcium-7
  • Rosuvastatin Impurity 28(Rosuvastatin EP Impurity F)
  • Rosuvastatin Calcium EP Impurity F
  • Rosuvastatin Impurity F
  • Rosuvastatin BEM
  • Rosuvastatin intermediate R-1
  • t-Butyl 6-[(1E)-2-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]ethenyl]-2,2-dimethyl-1,3-dioxane-4-acetate
  • 6-[(1E)-2-[4-(4-Fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]ethenyl]-2,2-dimethyl-1,3-dioxane-4-acetic acid 1,1-dime
  • 6-[(1E)-2-[4-(4-Fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]ethenyl]-2,2
  • Rosuvastatin Impurity 28
  • tert-Butyl 6-[(1E)-2-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]ethenyl]-2,2-dimethyl-1,3-dioxa
  • High quality ISO & BV Factory Tert-but...
  • (4R,6S)-6-[(1E)-2-[4-(4-Fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]ethenyl]-2,2-dimethyl-1,3-dioxane-4-acetic Acid 1,1-Dimethylethyl Ester
  • tert-Butyl 6-[(1E)-2-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]ethenyl]-2,2-dimethyl-1,3-dioxane-4-acetate [R1]
  • 1,1-dimethylethyl [(4R,6S)-6-[(E)-2-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)a
  • Rosuvastatin EP Impurity F (Rosuvastatin Acetonide t-Butyl Ester)
  • Tert-butyl-2-((4R,6S)-6-(E)-2-(4-(4-fluorophenyl)-6-Isopropyl-2-(N-methyl-D3-Methylsulfonamido)pyrimidin-5-yl)vinyl)-2,2-Dimethyl-1,3-dioxan-4-yl)acetate
  • tert-Butyl 6-[(1E)-2-[4-(4-fluorophenyl)-6-(1-methylethyl)-2...
  • tert-Butyl 6-[(1E)-2-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]ethenyl]-2,2-dimethyl-1,3-dioxane-4-acetate
  • ethyl(methylsulfonyl)amino]-5-pyrimidinyl]ethenyl]-2,2-dimethyl-1,3-dioxane-4-acetate
  • (4R,6S)-6-[(1E)-2-[4-(4-FLUOROPHENYL)-6-(1-METHYLETHYL)-2-[METHYL(METHYLSULFONYL)AMINO]-5-PYRIMIDINYL]ETHENYL]-2,2-DIMETHYL-1,3-DIOXANE-4-ACETIC ACID, 1,1-DIMETHYLETHYL ESTER
  • 6-[(1E)-2-[4-(4-Fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]ethenyl]-2,2-dimethyl-1,3-dioxane-4-acetic acid 1,1-dimethylethyl ester
  • Rosuvastatin intermediate R-2
  • tert-Butyl 2-((4R,6S)-6-((E)-2-(4-(4-fluorophenyl)-6-isopropyl-2-(N-MethylMethylsulfonaMido)pyriMidin-5-yl)vinyl)-2,2-diMethyl-1,3-dioxan-4-yl)acetate
  • R1 ROSUVASTATIN
  • tert-Butyl 6-[(1E)-2-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]ethenyl]-2,2-dimethyl-1,3-dioxane-4-acetat
  • Rosuvastatin R1
  • tert-Butyl6-[(1E)-2-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(metChemicalbookhylsulfonyl)amino]-5-pyrimidinyl]ethenyl]-2,2-dimethyl-1,3-dioxane-4-acetate
  • Rosuvastatin Related Compound C
  • 1,1-Dimethylethyl(4R,6S)-6-[(1E)-2-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]ethenyl]-2,2-dimethyl-1,3-dioxane-4-acetate
  • Rosuvastatin USP Related Compound C
  • R-1: Tert-Butyl6-[(1E)-2-[4-(4- fluorophenyl)-6-(1-methylethyl)-2- [methyl(methylsulfonyl) amino]-5- pyrimidinyl]ethenyl]-2,2-dimethyl-1,3- dioxane-4-acetate
  • (4R,6S,1E)-tert-Butyl 6-[2-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]ethenyl]-2,2-dimethyl-1,3-dioxane-4-acetate
  • Rosuvastatin Acetonide tertButyl Ester
  • Tert-butyl 2-((4R,6S)-6-((E)-2-(4-(4-flurophenyl)-6-isopropyl-2-(N- methylmethane sulfonamidoPyrimidin - 5-yl)vinyl)-2,2-dimethyl-1,3-dioxane-4-yl-)acetate (TIN)
  • Tertbutyl (E)-(6-{2-[4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methyl sulfonyl)amino pyrimidin-5-yl]vinyl}(4R,5R)-2,2-dimethyl[1,3]dioxane-4-yl)acetate
  • RSV Intermediate
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