Methyltestosteron

17-Methyltestosterone Struktur
58-18-4
CAS-Nr.
58-18-4
Bezeichnung:
Methyltestosteron
Englisch Name:
17-Methyltestosterone
Synonyma:
METHYLTESTOSTERONE;Androsten;17α-Methyltestosterone;Delatestryl;MESTERONE;METANDREN;Nu-man;ru24400;Syndren;Testora
CBNumber:
CB4213510
Summenformel:
C20H30O2
Molgewicht:
302.46
MOL-Datei:
58-18-4.mol

Methyltestosteron Eigenschaften

Schmelzpunkt:
162-168 °C(lit.)
alpha 
79 º (c=1, alcohol)
Siedepunkt:
383.47°C (rough estimate)
Dichte
1.0434 (rough estimate)
Brechungsindex
1.4800 (estimate)
Flammpunkt:
5 °C
storage temp. 
2-8°C
Löslichkeit
H2O: ≤0.5 mg/mL
Aggregatzustand
solid (photosensitive)
pka
15.13±0.60(Predicted)
Farbe
white
Wasserlöslichkeit
33.88mg/L(25 ºC)
Merck 
13,6148
BRN 
2057425
InChIKey
GCKMFJBGXUYNAG-HLXURNFRSA-N
CAS Datenbank
58-18-4(CAS DataBase Reference)
NIST chemische Informationen
17(Alpha)-methyl-delta4-androsten-17-(beta)-ol-3-one(58-18-4)
EPA chemische Informationen
Methyltestosterone (58-18-4)
Sicherheit
  • Risiko- und Sicherheitserklärung
  • Gefahreninformationscode (GHS)
Kennzeichnung gefährlicher T,Xn,F,Xi
R-Sätze: 45-63-22-20-19-11-61-60-36/37/38-38-10
S-Sätze: 53-36/37-45-24/25-22
RIDADR  3249
WGK Germany  3
RTECS-Nr. BV8400000
HazardClass  6.1(b)
PackingGroup  III
HS Code  29372900
Giftige Stoffe Daten 58-18-4(Hazardous Substances Data)
Toxizität man,TDLo,oral,39mg/kg/33W-I (39mg/kg),LIVER: "JAUNDICE, CHOLESTATIC",American Journal of Gastroenterology. Vol. 82, Pg. 461, 1987.
Bildanzeige (GHS) GHS hazard pictograms
Alarmwort Achtung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H350 Kann Krebs verursachen. Karzinogenität Kategorie 1A Achtung GHS hazard pictogramssrc="/GHS08.jpg" width="20" height="20" />
Sicherheit
P201 Vor Gebrauch besondere Anweisungen einholen.
P202 Vor Gebrauch alle Sicherheitshinweise lesen und verstehen.
P280 Schutzhandschuhe/Schutzkleidung/Augenschutz tragen.
P308+P313 BEI Exposition oder falls betroffen: Ärztlichen Rat einholen/ärztliche Hilfe hinzuziehen.
P405 Unter Verschluss aufbewahren.
P501 Inhalt/Behälter ... (Entsorgungsvorschriften vom Hersteller anzugeben) zuführen.

Methyltestosteron Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:

R45:Kann Krebs erzeugen.
R63:Kann das Kind im Mutterleib möglicherweise schädigen.
R22:Gesundheitsschädlich beim Verschlucken.
R20:Gesundheitsschädlich beim Einatmen.
R19:Kann explosionsfähige Peroxide bilden.
R11:Leichtentzündlich.
R61:Kann das Kind im Mutterleib schädigen.
R60:Kann die Fortpflanzungsfähigkeit beeinträchtigen.
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.

S-Sätze Betriebsanweisung:

S53:Exposition vermeiden - vor Gebrauch besondere Anweisungen einholen.
S36/37:Bei der Arbeit geeignete Schutzhandschuhe und Schutzkleidung tragen.
S45:Bei Unfall oder Unwohlsein sofort Arzt zuziehen (wenn möglich, dieses Etikett vorzeigen).
S24/25:Berührung mit den Augen und der Haut vermeiden.
S22:Staub nicht einatmen.

Beschreibung

Methyltestosterone is a synthetic analog of testosterone that possesses all of the properties of testosterone, exhibiting stimulatory action on the development of male sex organs and secondary sex characteristics, although it is not degraded by enzymes in the gastrointestinal tract, and therefore it can only be taken orally

Chemische Eigenschaften

white to slightly yellowish-white crystalline

Verwenden

Androgen. It has been used as an androgenic agent. Controlled substance (anabolic steroid).

Definition

ChEBI: A 17beta-hydroxy steroid that is testosterone bearing a methyl group at the 17alpha position.

Pharmakokinetik

The synthesis of 17α-methyltestosterone made available a compound that was orally active in daily doses between 10 and 50 mg, which is equivalent to a 400 mg oral dose of testosterone. The presence of a 17α alkyl group reduces susceptibility to hepatic oxidative metabolism, thereby increasing oral bioavailability by slowing metabolism. Following oral administration, methyltestosterone is well absorbed from the gastrointestinal tract, with a half-life of approximately 3 hours. This drug has the androgenic and anabolic activities of testosterone. Although orally active, it is more effective when administered sublingually. The alkylated oral androgens should be viewed as potentially hepatotoxic and should not be used.

Sicherheitsprofil

Poison by intraperitoneal route. Moderately toxic by ingestion. Human teratogenic effects by ingestion: developmental abnormalities of the urogenital system. Experimental teratogenic and reproductive effects. Human systemic effects: cholestatic jaundce, weight loss or decreased weight gain. Questionable human carcinogen producing liver tumors. A synthetic androgenic steroid. When heated to decomposition it emits acrid smoke and irritating fumes.

läuterung methode

This anabolic steroid is crystallised from hexane or hexane/*benzene. It has E1cm 1% 495-530 at 241nm (EtOH). The colour reaction with 2,4-dinitrophenyl hydrazine is used for assaying it. [Gornall & Macdonald J Biol Chem 201 279 1953.] In another colour reaction the sterone (1mg) in acetic acid (0.2ml) + 88% H3PO4 (2mL) is allowed to stand for 1hour when it becames fluorescent. After 1hour it is diluted with acetic acid (~3mL) and provides a strong yellow fluorescence with the intensity of 50-100 times that of estrone. [Stuart & Stuckey J Pharm Pharmacol 1 130 1949, Openauer Rec Trav Chim Pays-Bas 56 137 137, Beilstein 8 IV 1010.]

Methyltestosteron Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Methyltestosteron Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 358)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
qingdao future trading Co., Ltd
+86-13335044410 +86-13335044410
cui56813@163.com China 110 58
Shandong Huisheng Import & Export Co., Ltd.
+86-13176845580 +86-13176845580
da@zhongda-biotech.com China 232 58
Anhui Zhongda Biotechnology Co., Ltd
+8619956560829
justine@zhongda-biotech.com China 286 58
.GZ HONESTCHEM CO.,LTD
+86-15013270415 +86-15013270415
honestchemical@foxmail.com China 244 58
Shandong Hanjiang Chemical Co., Ltd
+86-0533-2066820 +8618369939125
hanson@sdhanjiang.com China 999 58
Shaanxi Xianhe Biotech Co., Ltd
+8617709210191
Jerry@xhobio.com China 737 58
Firsky International Trade (Wuhan) Co., Ltd
+8615387054039
admin@firsky-cn.com China 427 58
Anhui Yiao New Material Technology Co., Ltd
+86-18033737140 +86-17354101231
sales1@hbganmiao.com China 227 58
Anhui Zhongda Biotechnology Co., Ltd
+8615689548120
linda@zhongda-biotech.com China 193 58
Anhui Ruihan Technology Co., Ltd
+8617756083858
daisy@anhuiruihan.com China 973 58

58-18-4(Methyltestosteron)Verwandte Suche:


  • mtmucorettes
  • Neo-Hombreol-M
  • Neo-Homobreol (M)
  • NSC-9701
  • Nu-man
  • Oraviron
  • Orchisterone-M
  • Oreton Methyl
  • Oreton-M
  • oretonmethyl
  • ru24400
  • Steronyl
  • Synandrets
  • Synandrotabs
  • Syndren
  • testhormona
  • Testhormone
  • Testora
  • Testosterone, 17-methyl-
  • testoviron(tablet)
  • 17A-METHYLTESTOSTERONE--DEA*SCHEDULE III
  • 17A-METHYLTESTOSTERONE STANDARD*SOLUTION
  • 17-METHYLTESTOSTERONE--DEA SCHEDULE III
  • 17alpha-Methyltestosterone, USP
  • METHYLTESTOSTERONE 98+%
  • 17α-Methyl-Δ4-androsten-17β-ol-3-one
  • 17-Methyltestosterone, 97.0%-103.0%
  • Androst-4-en-3-one, 17beta-hydroxy-17-methyl-
  • Androst-4-en-3-one, 17-hydroxy-17-methyl-, (17beta)-
  • anertan(tablets)
  • Anertan, tablets
  • component of Estan
  • component of Estratest
  • component of Gynetone
  • component of Premarin with methyltestosterone
  • Dumogran
  • glossosterandryl
  • Glosso-Sterandryl
  • Hormale
  • M.T.Mucorettes
  • Malogen
  • Masenone
  • Mastestona
  • Metestone
  • Metrone
  • 17α-methyl-4-androsten-17β-ol-3-one
  • METHYLTESTOSTERONE,MICRONIZED,USP
  • METHYLTESTOSTERONE,POWDER,USP
  • 17beta-Hydroxy-17alpha-methylandrost-4-en-3-one
  • 17α-Methyl-4-androsten-17β-ol-3-one, 17β-Hydroxy-17α-methyl-4-androsten-3-one, Mesterone, Methyltestosterone
  • 17α-Methyl-4-androsten-17β-ol-3-one, 17β-Hydroxy-17α-methyl-4-androsten-3-one, Mesterone, Methyl testosteronum, Methyltestosterone
  • 17α-Methyl-4-androsten-17β-ol-3-one solution, 17α-Methyltestosterone solution, 17β-Hydroxy-17α-methyl-4-androsten-3-one solution, Mesterone solution, Methyltestosterone solution
  • (17)-17-hydroxy-17-methylandrost-4-ene-3-one
  • Androst-4-ene-17a-methyl-17b-ol-3-one
  • 17-Methyltestosterone,0%,97.0%-103.0%
  • Methyltestosterone CIII (200 mg)J1E3240.996mg/mg(dr)
  • 17α-Methyltestosterone,17α-Methyl-4-androsten-17β-ol-3-one, 17β-Hydroxy-17α-methyl-4-androsten-3-one, Mesterone, Methyltestosterone
  • Methyltestosterone CIII (200 mg)
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