SANGUINARINE CHLORIDE
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- CAS-Nr.
- 5578-73-4
- Englisch Name:
- SANGUINARINE CHLORIDE
- Synonyma:
- viadent;Sanguinarium;SANGUINARINE HCL;SANGUINARINE(SH);PSEUDOCHELERYTHRINE;SPECIOCILIATINE(SH);sanguinariumchloride;SANGUINARINE CHLORIDE;SANGUINARINE HCl hplc;Sanguinarine Choloride
- CBNumber:
- CB4228826
- Summenformel:
- C20H14ClNO4
- Molgewicht:
- 367.78
- MOL-Datei:
- 5578-73-4.mol
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SANGUINARINE CHLORIDE Eigenschaften
- Schmelzpunkt:
- 281-285°C
- storage temp.
- Inert atmosphere,2-8°C
- Löslichkeit
- methanol: 20 mg/mL, clear, orange
- Aggregatzustand
- Orange solid.
- Farbe
- Orange to Dark Orange
- Stabilität:
- Hygroscopic, Light Sensitive
Sicherheit
- Risiko- und Sicherheitserklärung
- Gefahreninformationscode (GHS)
| Kennzeichnung gefährlicher |
Xn |
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| R-Sätze: |
22 |
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| S-Sätze: |
36-26 |
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| WGK Germany |
3 |
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| RTECS-Nr. |
VP5220000 |
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| F |
10 |
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| HS Code |
29399990 |
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| Bildanzeige (GHS) |
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| Alarmwort |
Warnung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H302 |
Gesundheitsschädlich bei Verschlucken. |
Akute Toxizität oral |
Kategorie 4 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P270, P301+P312, P330, P501 |
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| Sicherheit |
| P264 |
Nach Gebrauch gründlich waschen. |
| P264 |
Nach Gebrauch gründlich waschen. |
| P270 |
Bei Gebrauch nicht essen, trinken oder rauchen. |
| P301+P312 |
BEI VERSCHLUCKEN: Bei Unwohlsein GIFTINFORMATIONSZENTRUM/Arzt/... (geeignete Stelle für medizinische Notfallversorgung vom Hersteller/Lieferanten anzugeben) anrufen. |
| P501 |
Inhalt/Behälter ... (Entsorgungsvorschriften vom Hersteller anzugeben) zuführen. |
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SANGUINARINE CHLORIDE Chemische Eigenschaften,Einsatz,Produktion Methoden
R-Sätze Betriebsanweisung:
R22:Gesundheitsschädlich beim Verschlucken.
S-Sätze Betriebsanweisung:
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
Verwenden
Sanguinarine chloride hydrate was tested for anti-schistosomal activities against
Schistosoma mansoni.
9 It was tested for anti-lipase activity against
Candida rugosa lipase.
10
Allgemeine Beschreibung
This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG
Biochem/physiol Actions
Sanguinarine is a benzophenanthridine alkaloid isolated from plants belonging to the family Papaveracea. It exhibits anti-bacterial, anti-fungal, anti-inflammatory and anti-cancer properties. It induces cell cycle arrest and sensitizes cancer cells to apoptosis by activating TNF-related apoptosis inducing ligand.6,7 It inhibits STAT3, MMP-2, MMP-9, interacts with glutathione, induces generation of ROS, disrupts the microtubule assembly and causes DNA damage resulting the death of the cancer cells.6,7,8
SANGUINARINE CHLORIDE Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
SANGUINARINE CHLORIDE Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
Global( 233)Lieferanten
5578-73-4()Verwandte Suche:
- SANGUINARINE CHLORIDE
- SANGUINARINE HCL
- PSEUDOCHELERYTHRINE
- PSEUDOCHELERYTHRINE CHLORIDE
- 13-METHYL-[1,3]BENZODIOXOLO[5,6-C]-1,3-DIOXOLO[4,5-I] PHENANTHRIDINIUM CHLORIDE
- Sanguinarine chloride, froM Macleaya cordata
- [1,3]Benzodioxolo[5,6-c]-1,3-dioxolo[4,5-i]phenanthridinium,13-methyl-, chloride (1:1)
- 3)benzodioxolo(5,6-c)-1,3-dioxolo(4,5-i)phenanthridinium,13-methyl-(chlo
- sanguinarinehydrochloride
- sanguinariumchloride
- viadent
- SANGUINARIN-CHLORID 97%
- Sanguinarium
- SANGUINARINE(SH)
- SANGUINARINE HCl hplc
- SPECIOCILIATINE(SH)
- Sanguinarine chloride hydrate, ≥98%(HPLC)
- Sanguinarine Chloride 5578-73-4
- Sanguinarine chloride, 98%, from Macleaya cordata
- Sanguinarine chloride, 98%, from Macleaya cordata (Willd.) R. Br.
- 13-Methyl-[1,3]dioxolo[4',5':4,5]benzo[1,2-c][1,3]dioxolo[4,5-i]phenanthridin-13-ium chloride
- Sanguinarine Choloride
- 13-Methyl-[1,3]dioxolo[4',5':4,5]benzo[1,2-c][1,3]dioxolo[4,5-i]phenanthridin-13-ium chloride
- Sanguinarine Chloride(AS)
- Sanguinarine chloride-RM
- 5578-73-4
- C20H14ClNO4
- C20H14NO4Cl
- Enzyme Inhibitors
- Enzyme Inhibitors by Type
- Enzymes, Inhibitors, and Substrates
- BioChemical
- Biochemicals and Reagents
- Cell Signaling and Neuroscience
- Cell Biology
- Ion Pump Inhibitors
- Ion Channels
- Monovalent Ion Channels
- Substrate Analogs
- Voltage-gated Ion Channels
- Inhibitors
- VIADENT
- Amines
- Aromatics
- Heterocycles
- Intermediates & Fine Chemicals
- Pharmaceuticals
- AlkaloidCancer Research
- Anti-proliferative AgentsVoltage-gated Ion Channels
- Ion Pump Inhibitors
- Biochemicals Found in Plants
- Chemopreventive Agents
- Monovalent Ion Channels
- Nutrition Research
- Alkaloids
