ANTIBIOTIC UCN-02

ANTIBIOTIC UCN-02 Struktur
121569-61-7
CAS-Nr.
121569-61-7
Englisch Name:
ANTIBIOTIC UCN-02
Synonyma:
UCN-02;UCN02,UCN 02;ANTIBIOTIC UCN-02;9,13-Epoxy-1H,9H-diindolo[1,2,3-gh:3',2',1'-lm]pyrrolo[3,4-j][1,7]benzodiazonin-1-one, 2,3,10,11,12,13-hexahydro-3-hydroxy-10-methoxy-9-methyl-11-(methylamino)-, (3S,9S,10R,11R,13R)-
CBNumber:
CB42446750
Summenformel:
C28H26N4O4
Molgewicht:
482.53
MOL-Datei:
121569-61-7.mol

ANTIBIOTIC UCN-02 Eigenschaften

Siedepunkt:
705.7±60.0 °C(Predicted)
Dichte
1.63±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
Löslichkeit
Soluble in DMSO
Aggregatzustand
solution in ethanol.
pka
12.25±0.70(Predicted)
Farbe
Colorless to light yellow

Sicherheit

ANTIBIOTIC UCN-02 Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

UCN-02 is a derivative of staurosporine and a stereoisomer of UCN-01 first isolated from a high staurosporine-producing Streptomyces culture as a minor co-metabolite. UCN-02 inhibits protein kinase C with a slightly reduced potency than UCN-01 (IC50 = 62 and 4.1 nM, for UNC-02 and UCN-01, respectively) and is cytotoxic to the growth of HeLa S3 cells.

Verwenden

UCN-02 is an indolocarbazole isolated from a high staurosporine-producing Streptomyces culture as a minor co-metabolite. Although less selective than its isomer UCN-01, UCN-02 exhibits comparable activity and probably acts by similar mechanisms.

ANTIBIOTIC UCN-02 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


ANTIBIOTIC UCN-02 Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 41)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
TargetMol Chemicals Inc.
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Career Henan Chemica Co
+86-0371-86658258 +8613203830695
laboratory@coreychem.com China 30253 58
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Aladdin Scientific
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Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627
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Lynnchem 86-(0)29-85992781 17792393971
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Novachemistry 44-20819178-90 02081917890
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Shenzhen Polymeri Biochemical Technology Co., Ltd. +86-400-002-6226 13028896684
sales@rrkchem.com China 56057 58
Fan De(Beijing) Biotechnology Co., Ltd. 15911056312
liming@bio-fount.com China 9730 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767
sales@chemegen.com China 11289 58

121569-61-7()Verwandte Suche:


  • UCN-02
  • ANTIBIOTIC UCN-02
  • 9,13-Epoxy-1H,9H-diindolo[1,2,3-gh:3',2',1'-lm]pyrrolo[3,4-j][1,7]benzodiazonin-1-one, 2,3,10,11,12,13-hexahydro-3-hydroxy-10-methoxy-9-methyl-11-(methylamino)-, (3S,9S,10R,11R,13R)-
  • UCN02,UCN 02
  • 121569-61-7
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