Angiogenesis Inhibitor Chemische Eigenschaften,Einsatz,Produktion Methoden
Allgemeine Beschreibung
A cell-permeable indolinone compound that displays anti-angiogenesis properties (30% inhibition of control at 10 μM in an
in vitro rat aortic ring model). The potency has been reported to be comparable to that of SU5416 (Cat. No. 676487; 22% inhibition of control at 10 μM). Acts as a moderate ATP-competitive inhibitor of hEGF-R tyrosine kinase activity (54% inhibition at 10 μM).
Biochem/physiol Actions
Cell permeable: yes
Angiogenesis Inhibitor Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte