GDC-0077

2060571-02-8

CAS-Nr.: 2060571-02-8

Englisch Name:: GDC-0077

Synonyma:: CPD1573;RG 6114;GDC-0077;RO 7113755;Inavolisib;GDC-0077 Inavolisib;Inavolisib (GDC-0077);GDC-0077; RG 6114; RO 7113755;Inavolisib (Synonyms: GDC-0077;Apoptosis,RG 6114,RG-6114,Phosphoinositide 3-kinase,Inhibitor,PI3K,Inavolisib,GDC 0077,GDC0077,inhibit

CBNumber:: CB43175543

Summenformel:: C18H19F2N5O4

Molgewicht:: 407.37

MOL-Datei:: 2060571-02-8.mol

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Eigenschaften Sicherheit Verwendungswort Produktionsfirma 64

GDC-0077 Eigenschaften

Siedepunkt:: 698.0±65.0 °C(Predicted)

Dichte: 1.63±0.1 g/cm3(Predicted)

storage temp.: Store at -20°C

Löslichkeit: DMSO:110.0(Max Conc. mg/mL);245.47(Max Conc. mM)

pka: 15.89±0.50(Predicted)

Aggregatzustand: Solid

Farbe: Off-white to yellow

InChIKey: SGEUNORSOZVTOL-CABZTGNLSA-N

SMILES: C(N)(=O)[C@@H](NC1C=C2OCCN3C=C(N4[C@H](C(F)F)COC4=O)N=C3C2=CC=1)C

Sicherheit

GDC-0077 Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Inavolisib, or GDC-0077, is a potent and selective PI3K inhibitor. GDC-0077 blocks an enzyme involved in cancer growth called PI3K. GDC0077 binds to and inhibits various members of the PI3K family, including activating mutations in the catalytic alpha isoform PIK3CA. PI3K inhibition prevents the activation of the PI3K-mediated signaling pathway and inhibits the growth and survival of PI3K-overexpressing tumor cells. The IUPAC name of this compound is (S)-2-((2-((S)-4-(difluoromethyl)-2-oxooxazolidin-3-yl)-5,6-dihydrobenzo[f]imidazo[1,2-d][1,4]oxazepin-9-yl)amino)propanamide.

GDC-0077 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

GDC-0077 Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 64)Lieferanten

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
Nantong HI-FUTURE Biology Co., Ltd.	+undefined18051384581	sales@chemhifuture.com	China	3136	58
Hubei Chuchang Biotech Co., Ltd.	+86-18727130788 +86-18727130788	info@chuchangbiotech.com	China	102	58
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32715	60
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19553	58
Neostar United (Changzhou) Industrial Co., Ltd.	+86-519-519-85557386	marketing1@neostarunited.com	China	12459	58
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	19892	58
Career Henan Chemica Co	+86-0371-86658258 15093356674;	laboratory@coreychem.com	China	30254	58
Zhejiang J&C Biological Technology Co.,Limited	+1-2135480471 +1-2135480471	sales@sarms4muscle.com	China	10522	58
Wuhan Topule Biopharmaceutical Co., Ltd	+8618327326525	masar@topule.com	China	8474	58
Aladdin Scientific	+1-+1(833)-552-7181	sales@aladdinsci.com	United States	57511	58

2060571-02-8()Verwandte Suche:

Testolacton

GDC-0077
Inavolisib
Propanamide, 2-[[2-[(4S)-4-(difluoromethyl)-2-oxo-3-oxazolidinyl]-5,6-dihydroimidazo[1,2-d][1,4]benzoxazepin-9-yl]amino]-, (2S)-
(2S)-2-[[2-[(4S)-4-(difluoromethyl)-2-oxo-1,3-oxazolidin-3-yl]-5,6-dihydroimidazo[1,2-d][1,4]benzoxazepin-9-yl]amino]propanamide
GDC-0077; RG 6114; RO 7113755
RO 7113755
RG 6114
CPD1573
Inavolisib (GDC-0077)
GDC-0077 Inavolisib
Apoptosis,RG 6114,RG-6114,Phosphoinositide 3-kinase,Inhibitor,PI3K,Inavolisib,GDC 0077,GDC0077,inhibit
(S)-2-[[2-[(S)-4-(Difluoromethyl)-2-oxo-3-oxazolidinyl]-5,6-dihydrobenzo[f]imidazo[1,2-d][1,4]oxazepin-9-yl]amino]propanamide
Inavolisib (Synonyms: GDC-0077
2060571-02-8