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REVEROMYCIN A

REVEROMYCIN A Struktur
134615-37-5
CAS-Nr.
134615-37-5
Englisch Name:
REVEROMYCIN A
Synonyma:
REVEROMYCIN A;ZESGNAJSBDILTB-OXVOKJAASA-N;Butanedioic acid, 1-[(2S,3R,6S,8R,9S)-3-butyl-8-[(2E,4E,6S,7S,8E)-9-carboxy-6-hydroxy-3,7-dimethyl-2,4,8-nonatrien-1-yl]-2-[(1E,3E)-4-carboxy-3-methyl-1,3-butadien-1-yl]-9-methyl-1,7-dioxaspiro[5.5]undec-3-yl] ester
CBNumber:
CB4443481
Summenformel:
C36H52O11
Molgewicht:
660.79
MOL-Datei:
134615-37-5.mol
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REVEROMYCIN A Eigenschaften

Siedepunkt:
849.0±65.0 °C(Predicted)
Dichte
1.21±0.1 g/cm3(Predicted)
storage temp. 
−20°C
Löslichkeit
DMF: soluble
Aggregatzustand
solid
pka
4.36±0.17(Predicted)
Farbe
tan

Sicherheit

WGK Germany  3

REVEROMYCIN A Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Reveromycin A, the dominant analogue of a complex of spiroketals isolated from a Streptomyces sp., is an inhibitor of the mitogenic activity of EGF. Reveromycin A is a G1 phase cell cycle inhibitor, selectively inhibiting isoleucyl-tRNA synthetase. Reveromycin A displays antiproliferative behaviour against human cell lines KB and K562, as well as potent antifungal activity. More recently it has been shown to induce apoptosis in osteoclasts thus inhibiting bone resorption.

REVEROMYCIN A Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

REVEROMYCIN A Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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134615-37-5()Verwandte Suche:

Vinblastinsulfat 5,6,7,8-Tetramethoxy-2-(4-methoxyphenyl)-4-benzopyron 3,5,7-Trihydroxy-2-(4-hydroxy-3,5-dimethoxyphenyl)-1-benzopyryliumchlorid (S)-α-Amino-3-hydroxy-4-oxo-1(4H)-pyridylpropionsure (2E,6E)-Nona-2,6-dien-1-al (2E,4E)-Dodeca-2,4-dienal
  • REVEROMYCIN A
  • ZESGNAJSBDILTB-OXVOKJAASA-N
  • Butanedioic acid, 1-[(2S,3R,6S,8R,9S)-3-butyl-8-[(2E,4E,6S,7S,8E)-9-carboxy-6-hydroxy-3,7-dimethyl-2,4,8-nonatrien-1-yl]-2-[(1E,3E)-4-carboxy-3-methyl-1,3-butadien-1-yl]-9-methyl-1,7-dioxaspiro[5.5]undec-3-yl] ester
  • 134615-37-5
  • C36H52O11
  • BioChemical
  • Antibiotics
  • Antibiotics A to Z
  • Antibiotics N-S
  • Epidermal Growth Factor Receptor (EGFR)Antibiotics
  • Interferes with Protein Synthesis
  • Antibiotics
  • Antibiotics A to
  • Antibiotics by Application
  • Antibiotics N-SAntibiotics
  • AntifungalAntibiotics
  • Mechanism of Action
  • Receptor Tyrosine Kinase Inhibitors
  • Spectrum of Activity
  • Antineoplastic and Immunosuppressive AntibioticsReceptor Tyrosine Kinase Biology
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