4'-N-OCTYLBIPHENYL-4-CARBOXYLIC ACID

59662-49-6

CAS-Nr.: 59662-49-6

Englisch Name:: 4'-N-OCTYLBIPHENYL-4-CARBOXYLIC ACID

Synonyma:: 8BCA;AC 55649;AC55649,AC 55649;RARECHEM AL BO 1323;4-(4-Octylphenyl)-benzoic acid;4-OCTYL-4'-BIPHENYLCARBOXYLIC ACID;4'-OCTYL-4-BIPHENYLCARBOXYLIC ACID;4-N-OCTYLBIPHENYL-4'-CARBOXYLIC ACID;4'-N-OCTYLBIPHENYL-4-CARBOXYLIC ACID;4'-Octyl[1,1'-biphenyl]-4-carboxylic acid

CBNumber:: CB4462046

Summenformel:: C21H26O2

Molgewicht:: 310.43

MOL-Datei:: 59662-49-6.mol

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Eigenschaften Sicherheit Verwendungswort Produktionsfirma 67

4'-N-OCTYLBIPHENYL-4-CARBOXYLIC ACID Eigenschaften

Schmelzpunkt:: 148-152 °C(Solv: dichloromethane (75-09-2))

Siedepunkt:: 462.0±34.0 °C(Predicted)

Dichte: 1.037±0.06 g/cm3(Predicted)

storage temp.: Store at +4°C

Löslichkeit: DMSO: >7mg/mL

Aggregatzustand: solid

pka: 4.23±0.10(Predicted)

Farbe: White to off-white

Sicherheit

Risiko- und Sicherheitserklärung
Gefahreninformationscode (GHS)

WGK Germany	3

Bildanzeige (GHS)

Alarmwort

Warnung

Gefahrenhinweise

Code	Gefahrenhinweise	Gefahrenklasse	Abteilung	Alarmwort	Symbol	P-Code
H413	Kann für Wasserorganismen schädlich sein, mit langfristiger Wirkung.	Langfristig (chronisch) gewässergefährdend	Kategorie 4

Sicherheit

4'-N-OCTYLBIPHENYL-4-CARBOXYLIC ACID Chemische Eigenschaften,Einsatz,Produktion Methoden

Biologische Aktivität

Potent, isoform-selective RAR β 2 receptor agonist (pEC 50 values are 6.9, 5.7 and 5.6 at RAR β 2, RAR β 1 and RAR α respectively) that displays 100-fold selectivity versus other retinoid receptors. Inhibits proliferation of the breast cancer cell line MCF-7.

Biochem/physiol Actions

AC-55649 is a subtype selective RAR (RARβ2) agonist. AC-55649 is a potent, orally available isoform selective Retinoic Acid Receptor β2. AC-55649 has high selectivity, 99% for RARβ2 and 31% for RARβ1. When compared to the gold standard AM-580 (Cat. No A8843), both isoform receptors were 100%. AC-55649 has a potent EC50 of 6.9 μM compared to an EC50 of 7.7 μM for AM-580.

4'-N-OCTYLBIPHENYL-4-CARBOXYLIC ACID Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

4'-N-OCTYLBIPHENYL-4-CARBOXYLIC ACID Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 67)Lieferanten

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	19892	58
Career Henan Chemica Co	+86-0371-86658258 +8613203830695	laboratory@coreychem.com	China	30253	58
Aladdin Scientific	+1-+1(833)-552-7181	sales@aladdinsci.com	United States	57511	58
Wuhan Jingkang en Biomedical Technology Co., Ltd	+8613720134139	orders@jknbiochem.com	China	4692	58
Amadis Chemical Company Limited	571-89925085	sales@amadischem.com	China	131980	58
3B Pharmachem (Wuhan) International Co.,Ltd.	821-50328103-801 18930552037	3bsc@sina.com	China	15848	69
Capot Chemical Co., Ltd	+86 (0) 571 85 58 67 18	sales@capotchem.com	China	18217	66
Sigma-Aldrich	021-61415566 800-8193336	orderCN@merckgroup.com	China	51471	80
Shanghai Lollane Biological Technology Co.,Ltd.	021-52996696，15000506266 15000506266		China	4197	55
EMMX Biotechnology LLC	888-539-0666	info@emmx.com	United States	8449	60

59662-49-6()Verwandte Suche:

4-Hexylbiphenyl Biphenyl-4-carbonsure 4-Methyl-4'-pentyl-1,1'-biphenyl

4'-N-OCTYLBIPHENYL-4-CARBOXYLIC ACID
4-N-OCTYLBIPHENYL-4'-CARBOXYLIC ACID
4'-OCTYL-[1,1'-BIPHENYL]-4-CARBOXYLIC ACID
4'-OCTYL-4-BIPHENYLCARBOXYLIC ACID
4-OCTYL-4'-BIPHENYLCARBOXYLIC ACID
8BCA
AC 55649
4-(4-Octylphenyl)-benzoic acid
4′-Octyl-4-biphenylcarboxylic acid, 4′-n-octylbiphenyl-4-carboxylic acid
RARECHEM AL BO 1323
[1,1'-Biphenyl]-4-carboxylic acid, 4'-octyl-
AC55649,AC 55649
4'-Octyl[1,1'-biphenyl]-4-carboxylic acid
59662-49-6
Biphenyl & Diphenyl ether