4'-Chlor-3,5-dimethoxy-4-(2-morpholinoethoxy)benzophenonhydrochlorid

4'-chloro-3,5-dimethoxy-4-(2-morpholinoethoxy)benzophenone hydrochloride Struktur
31848-02-9
CAS-Nr.
31848-02-9
Bezeichnung:
4'-Chlor-3,5-dimethoxy-4-(2-morpholinoethoxy)benzophenonhydrochlorid
Englisch Name:
4'-chloro-3,5-dimethoxy-4-(2-morpholinoethoxy)benzophenone hydrochloride
Synonyma:
Morclofone hydrochloride;4'-chloro-3,5-dimethoxy-4-(2-morpholinoethoxy)benzophenone hydrochloride
CBNumber:
CB4938327
Summenformel:
C21H25Cl2NO5
Molgewicht:
442.3329
MOL-Datei:
31848-02-9.mol

4'-Chlor-3,5-dimethoxy-4-(2-morpholinoethoxy)benzophenonhydrochlorid Eigenschaften

Sicherheit

4'-Chlor-3,5-dimethoxy-4-(2-morpholinoethoxy)benzophenonhydrochlorid Chemische Eigenschaften,Einsatz,Produktion Methoden

Originator

Plausitin,Carlo Erba,Italy,1975

Manufacturing Process

Sodium methoxide (1.2 g) in dimethylformamide (150 ml) was stirred with 3,5-dimethoxy-4'-chloro-4-hydroxybenzophenone (6 g) in dimethylformamide (50 ml), for 2 hours at 120°C. The reaction mixture was then treated with β- morpholinoethyl chloride (3.4 g) and heated for 1 hour at 140C, then evaporated to dryness, and treated with water to give a solid material. The mixture was filtered, washed and crystallized from cyclohexane to give 3,5- dimethoxy-4'-chloro-4-(β-morpholinoethoxy)-benzophenone (6.5 g), MP 91°C to 92°C. The product was then reacted at about 0°C with gaseous hydrogen chloride in ether to give, after crystallization from isopropanol, the corresponding hydrochloride which had a MP of 187.9°C.

Therapeutic Function

Antitussive

4'-Chlor-3,5-dimethoxy-4-(2-morpholinoethoxy)benzophenonhydrochlorid Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


4'-Chlor-3,5-dimethoxy-4-(2-morpholinoethoxy)benzophenonhydrochlorid Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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31848-02-9(4'-Chlor-3,5-dimethoxy-4-(2-morpholinoethoxy)benzophenonhydrochlorid)Verwandte Suche:


  • 4'-chloro-3,5-dimethoxy-4-(2-morpholinoethoxy)benzophenone hydrochloride
  • Morclofone hydrochloride
  • 31848-02-9
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