6-hydroxydexamethasone

55879-47-5

CAS-Nr.: 55879-47-5

Englisch Name:: 6-hydroxydexamethasone

Synonyma:: 6-hydroxydexamethasone;6β-hydroxy Dexamethasone;Dexamethasone Impurity 12;Dexamethasone 6β-Hydroxy Impurity;Dexamethasone 6beta-Hydroxy Impurity;6-Hydroxydexamethasone Solution, 100ppm;(6R,8S,9R,10S,11S,13S,14S,16R,17R)-9-fluoro-6,11,17-trihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one

CBNumber:: CB51341435

Summenformel:: C22H29FO6

Molgewicht:: 408.46

MOL-Datei:: 55879-47-5.mol

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Eigenschaften Sicherheit Verwendungswort Produktionsfirma 29

6-hydroxydexamethasone Eigenschaften

Schmelzpunkt:: 259-262°C

Siedepunkt:: 613.2±55.0 °C(Predicted)

Dichte: 1.38±0.1 g/cm3(Predicted)

storage temp.: -20°C Freezer

Löslichkeit: Dioxane (Very Slightly, Sonicated), Methanol (Slightly)

Aggregatzustand: Solid

pka: 12.06±0.70(Predicted)

Farbe: White to Light Yellow

Sicherheit

6-hydroxydexamethasone Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

6β-hydroxy Dexamethasone is a metabolite of dexamethasone (Item Nos. 11015 | 20340) that is more hydrophilic than the parent compound. Dexamethasone is metabolized by CYP3A4; therefore, quantification of the dexamethasone metabolites, 6α- and 6β-hydroxy dexamethasone, can be used to determine CYP3A4 enzyme activity in humans. The formation of 6-hydroxy dexamethasone metabolites is species-specific, with hamsters producing the highest amount. In rats, dexamethasone hydroxylation is sex-specific, with male rats producing metabolites in similar ratios to humans and female rats producing fewer hydroxylated metabolites than male rats.

Chemische Eigenschaften

Off-White Solid

Verwenden

The hydrophilic metabolite of Dexamethasone (D298800).

6-hydroxydexamethasone Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

6-hydroxydexamethasone Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 29)Lieferanten

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
Standardpharm Co. Ltd.	86-714-3992388	overseasales1@yongstandards.com	United States	14336	58
China National Standard Pharmaceutical Corporation Limited	+8615391658522	overseasales@yongstandards.com	China	11927	58
J & K SCIENTIFIC LTD.	010-82848833 400-666-7788	jkinfo@jkchemical.com	China	96815	76
Chemsky（shanghai）International Co.,Ltd.	021-50135380	shchemsky@sina.com	China	32344	50
S.Z. PhyStandard Bio-Tech. Co., Ltd.	0755-83725681-603		China	4505	50
Clearsynth Labs Limited	+91-22-26355700	info@clearsynth.com	India	9685	58
Alta Scientific Co., Ltd.	022-6537-8550 15522853686	sales@altasci.com.cn	China	4515	55
BOC Sciences	16314854226	info@bocsci.com	United States	9926	65
Shanghai EFE Biological Technology Co., Ltd.	021-65675885 18964387627	info@efebio.com	China	9707	58
Shenzhen Polymeri Biochemical Technology Co., Ltd.	+86-400-002-6226 13028896684	sales@rrkchem.com	China	56060	58

55879-47-5()Verwandte Suche:

Desoximetason Dexamethason Dexamethason-21-acetat Betamethason 17-α,21-Dihydroxy-16-α-methylpregna-1,4,9(11)-trien-3,20-dion-21-acetat 9-Fluor-11β,17,21-trihydroxy-16α-methylpregna-1,4-dien-3,20-dion-17,21-di(propionat) 9β,11β-Epoxy-17,21-dihydroxy-16α-methylpregna-1,4-dien-3,20-dion 17,21-Dihydroxy-16α-methylpregna-1,4,9(11)-trien-3,20-dion 9-Fluor-11β,17,21-trihydroxy-16β-methylpregna-1,4-dien-3,20-dion-21-(hydrogenphosphonat)

6-hydroxydexamethasone
Dexamethasone 6β-Hydroxy Impurity
Dexamethasone Impurity 12
6-Hydroxydexamethasone Solution, 100ppm
(6R,8S,9R,10S,11S,13S,14S,16R,17R)-9-fluoro-6,11,17-trihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one
Dexamethasone 6beta-Hydroxy Impurity
6β-hydroxy Dexamethasone
55879-47-5
C22H29FO6
Intermediates & Fine Chemicals
Metabolites & Impurities
Pharmaceuticals
Steroids