DISIALOGANGLIOSIDE GD1B 2NA Chemische Eigenschaften,Einsatz,Produktion Methoden
S-Sätze Betriebsanweisung:
S22:Staub nicht einatmen.
S24/25:Berührung mit den Augen und der Haut vermeiden.
Beschreibung
Ganglioside G
D1b is an acidic glycosphingolipid that contains two sialic acid residues linked to an inner galactose unit. It is a component of plasma membranes where it packs densely with cholesterol to form lipid microdomains that modulate both intra- and intercellular signaling events. The concentration of ganglioside G
D1b in human brain increases with age, constituting 7.85% of total sialic acid in the brain of 0- to 10-year-old subjects and 20.29% in 11- to 30-year-old subjects. Ganglioside G
D1b levels are positively correlated with pilocytic astrocytoma tumor grade, and G
D1b has been detected in various other gliomas, including primitive neuroectodermal tumors, glioblastomas, and anaplastic astrocytomas. Ganglioside G
D1b mixture contains ganglioside G
D1b molecular species with C18:1 and C20:1 fatty acyl chains.
Verwenden
Ganglioside GD1b Disodium Salt (Bovine Brain) is a ganglioside, major constituents of neuronal cell membranes and endoplasmic reticulum that have been shown to modulate cell signal transduction.
Allgemeine Beschreibung
Gangliosides are major constituents of neuronal cell membranes and endoplasmic reticulum; contain a sialated polysaccharide chain linked to ceramide through a β-glycosidic linkage; for classification of gangliosides see Svennerholm, L., et al. (eds.),
Structure and Function of Gangliosides, New York, Plenum, 1980.
DISIALOGANGLIOSIDE GD1B 2NA Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
