trans-Cyclooctene-maleimide

trans-Cyclooctene-maleimide Struktur
1609659-01-9
CAS-Nr.
1609659-01-9
Englisch Name:
trans-Cyclooctene-maleimide
Synonyma:
TCO-PEG3-maleimide;(4E)-TCO-PEG3-Maleimide;trans-Cyclooctene-maleimide;Trans-Cyclooctene-PEG3-Maleimide,TCO-PEG3-Maleimide;6,9,12-Trioxa-2,16-diazanonadecanoic acid, 19-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-17-oxo-, 4-cycloocten-1-yl ester
CBNumber:
CB52925335
Summenformel:
C26H41N3O8
Molgewicht:
523.62
MOL-Datei:
1609659-01-9.mol

trans-Cyclooctene-maleimide Eigenschaften

Siedepunkt:
717.1±60.0 °C(Predicted)
Dichte
1.19±0.1 g/cm3(Predicted)
storage temp. 
-20°C
pka
12.38±0.46(Predicted)

Sicherheit

WGK Germany  3

trans-Cyclooctene-maleimide Chemische Eigenschaften,Einsatz,Produktion Methoden

Biochem/physiol Actions

Maleimide (thiol reactive) functionalized trans-cyclooctene derivative for incorporation of the cyclooctene moiety into thiol containing compounds or biomolecules. Trans-cyclooctenes are useful in strain-promoted copper-free click chemistry cycloaddition reactions with 1; 2; 4; 5-tetrazines. This cyclooctene will react with tetrazine functionalized compounds or biomolecules without the need for a catalyst to result in a stable covalent linkage. The 4+2 inverse electron demand Diels-Alder cycloaddition between trans-cyclooctene and tetrazines is the fastest biologically compatible ligation technology reported and has had many applications in biological labeling and imaging. The PEG spacer allows for increased water solubility; less aggregation and an increased distance between the thiol to be modified and the reactive alkene.

trans-Cyclooctene-maleimide Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


trans-Cyclooctene-maleimide Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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  • TCO-PEG3-maleimide
  • trans-Cyclooctene-maleimide
  • 6,9,12-Trioxa-2,16-diazanonadecanoic acid, 19-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-17-oxo-, 4-cycloocten-1-yl ester
  • Trans-Cyclooctene-PEG3-Maleimide,TCO-PEG3-Maleimide
  • (4E)-TCO-PEG3-Maleimide
  • 1609659-01-9
  • C26H41N3O8
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