BI-7273

1883429-21-7

CAS-Nr.: 1883429-21-7

Englisch Name:: BI-7273

Synonyma:: BI273;BI-7273;CS-2327;BI 7273;BI7273;inhibit,Inhibitor,Epigenetic Reader Domain,BI7273,BI-7273,BI 7273;4-(4-((dimethylamino)methyl)-2,6-dimethoxyphenyl)-2-methyl-2,7-naphthyridin-1(2H)-one;2,7-Naphthyridin-1(2H)-one, 4-[4-[(dimethylamino)methyl]-3,5-dimethoxyphenyl]-2-methyl-

CBNumber:: CB53128809

Summenformel:: C20H23N3O3

Molgewicht:: 353.41

MOL-Datei:: 1883429-21-7.mol

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Eigenschaften Sicherheit Verwendungswort Produktionsfirma 55

BI-7273 Eigenschaften

Siedepunkt:: 509.2±50.0 °C(Predicted)

Dichte: 1.189±0.06 g/cm3(Predicted)

storage temp.: Store at -20°C

Löslichkeit: ≥35.3 mg/mL in DMSO with gentle warming; ≥1.99 mg/mL in EtOH with ultrasonic; ≥8.74 mg/mL in H2O

Aggregatzustand: solid

pka: 8.32±0.28(Predicted)

Farbe: White to off-white

Sicherheit

BI-7273 Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

BI-7273 is a potent BRD9 bromodomain inhibitor (K_d = 15.4 nM; IC₅₀ = 19 nM) that less effectively inhibits the functionally and structurally related BRD7 bromodomain (IC₅₀ = 117 nM). It is without effect against the bromodomains of BRD2 and BRD4, as well as a panel of kinases. BI-7273 inhibits the growth of EOL-1 acute myeloid leukemia cells in vitro (EC₅₀ = 1.4 μM).

BI-7273 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

BI-7273 Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 55)Lieferanten

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
HANGZHOU CLAP TECHNOLOGY CO.,LTD	86-571-88216897,88216896 13588875226	sales@hzclap.com	CHINA	6313	58
Zhejiang J&C Biological Technology Co.,Limited	+1-2135480471 +1-2135480471	sales@sarms4muscle.com	China	10522	58
InvivoChem	+1-708-310-1919 +1-13798911105	sales@invivochem.cn	United States	6393	58
TargetMol Chemicals Inc.	+1-781-999-5354	support@targetmol.com	United States	19973	58
ShenZhen Trendseen Biological Technology Co.,Ltd.	13417589054	trendseenbio@gmail.com	China	11681	58
Wuhan Topule Biopharmaceutical Co., Ltd	+8618327326525	masar@topule.com	China	8474	58
Aladdin Scientific	+1-+1(833)-552-7181	sales@aladdinsci.com	United States	57511	58
Amadis Chemical Company Limited	571-89925085	sales@amadischem.com	China	131980	58
Shanghai Boyle Chemical Co., Ltd.		sales@boylechem.com	China	2923	55
Haoyuan Chemexpress Co., Ltd.	021-58950125	info@chemexpress.com	China	7553	61

BI-7273
BI273
2,7-Naphthyridin-1(2H)-one, 4-[4-[(dimethylamino)methyl]-3,5-dimethoxyphenyl]-2-methyl-
CS-2327
BI 7273;BI7273
inhibit,Inhibitor,Epigenetic Reader Domain,BI7273,BI-7273,BI 7273
4-(4-((dimethylamino)methyl)-2,6-dimethoxyphenyl)-2-methyl-2,7-naphthyridin-1(2H)-one
1883429-21-7
1883429-21-9