ANTI-INOSITOL 1,4,5-TRISPHOSPHATE RECEPTOR (TYPE-I)

ANTI-INOSITOL 1,4,5-TRISPHOSPHATE RECEPTOR (TYPE-I) Chemische Eigenschaften,Einsatz,Produktion Methoden

Allgemeine Beschreibung

The gene ITPR1 (inositol 1,4,5-triphosphate receptor type 1) encodes an intracellular receptor that binds to inositol 1,4,5 trisphosphate. It is localized to membranes of endoplasmatic or sarcoplasmatic (in muscle cells) reticulum. The gene is mapped to human chromosome 3p26.

Biochem/physiol Actions

The ligand-gated calcium channel encoded by the gene ITPR1 (inositol 1,4,5-triphosphate receptor type 1) is stimulated upon binding to its ligand inositol 1,4,5-triphosphate, and mediates intracellular calcium signaling. It facilitates the release of Ca2+ from endoplasmic reticulum and modulates intracellular Ca2+ concentration. This is a crucial mechanism in the initial stages of myoblast differentiation. Mutations in this gene have been associated with sporadic infantile-onset cerebellar ataxia.

ANTI-INOSITOL 1,4,5-TRISPHOSPHATE RECEPTOR (TYPE-I) Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

ANTI-INOSITOL 1,4,5-TRISPHOSPHATE RECEPTOR (TYPE-I) Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
Riedel-de Haen AG	--		United States	6825	87
SIGMA-RBI	--		Switzerland	6913	91
A.G. Scientific, Inc.	--	support@agscientific.com	United States	1066	71
ABR-Affinity BioReagents	--	affinity@bioreagents.com	United States	489	73
BIOMOL INTERNATIONAL, LP	--	info@biomol.com	United States	1503	77
Alexis Corporation	--	alexis-ch@alexis-corp.ch	Switzerland	3599	74
Fluorochem Ltd.	--	enquiries@fluorochem.co.uk	United Kingdom	6406	74

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• POLYCLONAL ANTIBODY TO INOSITOL 1,4,5-TRIPHOSPHATE RECEPTOR TYPE I
• ANTISERUM TO INS(1,4,5)P3, RECEPTOR TYPE I
• ANTI-INOSITOL 1,4,5-TRISPHOSPHATE RECEPTOR (TYPE-I)
• ANTI-INOSITOL 1,4,5-TRIPHOSPHATE RECEPTOR (TYPE I)
• ANTI-IP3R-I
• ANTI-IP3 RECEPTOR (TYPE-I)
• IP3 RECEPTOR TYPE I
• Anti-Inositol 1,4,5-Triphosphate Receptor (Type I) antibody produced in rabbit
• Alphabetical Index
• Antibodies to Calcium ChannelsAntibodies
• Antibodies to Ion Channels
• Antibodies to Voltage-Gated Ion Channels
• I