943319-87-7

CAS-Nr.: 943319-87-7

Englisch Name:: 943319-87-7

Synonyma:: AP24567;AP-24567;Ponatinib N-Desmethyl;N-Desmethyl ponatinib;Ponatinib N-Desmethyl Analog;Ponatinib Active Metabolite A;Ponatinib Active Metabolite AP24567(M42);Benzamide, 3-(2-imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-[4-(1-piperazinylmethyl)-3-(trifluoromethyl)phenyl]-

CBNumber:: CB54660663

Summenformel:: C28H25F3N6O

Molgewicht:: 518.53

MOL-Datei:: 943319-87-7.mol

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Eigenschaften Sicherheit Verwendungswort Produktionsfirma 15

943319-87-7 Eigenschaften

Dichte: 1.32±0.1 g/cm3(Predicted)

Löslichkeit: DMSO (Slightly), Methanol (Slightly)

Aggregatzustand: Solid

pka: 12.99±0.70(Predicted)

Farbe: Pale Yellow to Light Yellow

Sicherheit

943319-87-7 Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Ponatinib Active Metabolite AP24567(M42) is a research reagent applied in pharmaceuticals and cancer treatment. Ponatinib Active Metabolite AP24567(M42) is an analog of Ponatinib (P688250) which is a tyrosine kinase inhibitors (TKI) and used to treat chronic myeloid leukemia (CML) (1,2,3). Ponatinib (P688250) is also used in combination with other drugs, such as forskolin, to combat TKI resistance in patient with CML (3), targeted drug in small-cell lung cancer. Potent FAK inhibitor. FGFR/VEGFR/Bcr-Abl inhibitor It is a COVID19-related research product.

943319-87-7 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

943319-87-7 Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 15)Lieferanten

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
TargetMol Chemicals Inc.	+1-781-999-5354	support@targetmol.com	United States	19973	58
Beijing Comparison Pharmaceutical Technology Co., Ltd	010-010-52878169 15801002657	sales@bjcomparison.com	China	4914	58
Shanghai Kewel Chemical Co., Ltd.	021-64609169 18901607656	greensnown@163.com	China	9911	50
Nanjing XiZe Biotechnology CO., Ltd.	025-66023220 0086-15250997978	1511893459@qq.com	China	7851	55
Shanghai CR Corporation Limited	021-80270511; 4006653949	fred.wen@crcorporation.cn	China	10047	58
TOSUN PHARM	020-61855200 13326451905	260366801@qq.com	China	7743	58
Beijing xinyanhui pharmaceutical research and development co., LTD	13969155946	1461866103@qq.com	China	16111	58
QUALITY CONTROL SOLUTIONS LTD.	13670046396	ORDERS@QCSRM.COM	China	18899	58
Changzhou Bojia Biomedical Technology Co., Ltd.	2122619822	czbjpharma@126.com	China	18488	58
TargetMol Chemicals Inc.	4008200310	marketing@tsbiochem.com	China	18779	58

N-Desmethyl ponatinib
Ponatinib N-Desmethyl
Benzamide, 3-(2-imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-[4-(1-piperazinylmethyl)-3-(trifluoromethyl)phenyl]-
Ponatinib Active Metabolite AP24567(M42)
AP24567
AP-24567
Ponatinib Active Metabolite A
Ponatinib N-Desmethyl Analog
943319-87-7