2,6-DICHLORO-5-FLUORONICOTINAMIDE
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- CAS-Nr.
- 113237-20-0
- Englisch Name:
- 2,6-DICHLORO-5-FLUORONICOTINAMIDE
- Synonyma:
- 2,6-DICHLORO-5-FLUOROPYRIDINE-3-CARBOXAMIDE;2,6-Dichloro-5-fluoropyridine-3-carboxamide, 3-Carbamoyl-2,6-dichloro-5-fluoropyridine;CPD2809-A1;Sotorasib Impurity 1;Olutasidenib Impurity 32;2,6-DICHLORO-5-FLUORONICOTIMIDE;2,6-DICHLORO-5-FLUORONICOTINAMIDE;2,6-Dichloro-5-fluoronicotinamide97%;2,6-Dichloro-5-fluoronicotinamide 97%;2,6-Dichloro-3-formamide-5-fluoropyridine
- CBNumber:
- CB5735729
- Summenformel:
- C6H3Cl2FN2O
- Molgewicht:
- 209.01
- MOL-Datei:
- 113237-20-0.mol
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2,6-DICHLORO-5-FLUORONICOTINAMIDE Eigenschaften
- Schmelzpunkt:
- 160-162
- Siedepunkt:
- 259.0±40.0 °C(Predicted)
- Dichte
- 1.614±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- Aggregatzustand
- crystalline solid
- pka
- 13.36±0.50(Predicted)
- Farbe
- White
- InChI
- InChI=1S/C6H3Cl2FN2O/c7-4-2(6(10)12)1-3(9)5(8)11-4/h1H,(H2,10,12)
- InChIKey
- ZVYNUGSPFZCYEV-UHFFFAOYSA-N
- SMILES
- C1(Cl)=NC(Cl)=C(F)C=C1C(N)=O
2,6-DICHLORO-5-FLUORONICOTINAMIDE Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
2,6-Dichloro-5-fluoronicotinamide is a fluorinated pharmaceutical intermediate compound used in the synthesis of Sotorasib and AMG 510. Sotorasib is a RAS GTPase family inhibitor used for the treatment of KRAS-mutated solid tumours including non-small cell lung cancer (NSCLC) and colorectal cancer.
2,6-DICHLORO-5-FLUORONICOTINAMIDE Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
2,6-DICHLORO-5-FLUORONICOTINAMIDE Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
Global( 191)Lieferanten
113237-20-0()Verwandte Suche:
- 3-PyridinecarboxaMide, 2,6-dichloro-5-fluoro-
- 2,6-Dichloro-5-fluoronicotinamide97%
- 2,6-DICHLORO-5-FLUORONICOTINAMIDE
- 2,6-Dichloro-5-fluoronicotinamide 97%
- CPD2809-A1
- 2,6-DICHLORO-5-FLUORONICOTIMIDE
- 2,6-dichloro-3-carboxamide-5-fluoropyridine
- 2,6-DICHLORO-5-FLUORONICOTINAMIDE ISO 9001:2015 REACH
- 2,6-Dichloro-5-fluoropyridine-3-carboxamide, 3-Carbamoyl-2,6-dichloro-5-fluoropyridine
- 2,6-DICHLORO-5-FLUOROPYRIDINE-3-CARBOXAMIDE
- 2,6-Dichloro-3-formamide-5-fluoropyridine
- Sotorasib Impurity 1
- Olutasidenib Impurity 32
- 113237-20-0
- C6H3Cl2FN2O
- 113237-20-0