4-[[N-(IMIDAZOL-4-YL)METHYLENEAMINO]-2-(1-NAPHTHYL)BENZOYL]LEUCINE METHYL ESTER

191102-87-1

CAS-Nr.: 191102-87-1

Englisch Name:: 4-[[N-(IMIDAZOL-4-YL)METHYLENEAMINO]-2-(1-NAPHTHYL)BENZOYL]LEUCINE METHYL ESTER

Synonyma:: GGTI-2147;GGTI-2147 (GGTI2147);TUQRZGWNDBXSNP-SANMLTNESA-N;Geranylgeranyl transferase inhibitor-2147;4-[[N-(IMIDAZOL-4-YL)METHYLENEAMINO]-2-(1-NAPHTHYL)BENZOYL]LEUCINE METHYL ESTER;L-Leucine, N-[4-[(1H-imidazol-5-ylmethyl)amino]-2-(1-naphthalenyl)benzoyl]-, methyl ester

CBNumber:: CB5766770

Summenformel:: C28H30N4O3

Molgewicht:: 470.56

MOL-Datei:: Mol file

Request For Quotation

Eigenschaften Sicherheit Verwendungswort Produktionsfirma 30

4-[[N-(IMIDAZOL-4-YL)METHYLENEAMINO]-2-(1-NAPHTHYL)BENZOYL]LEUCINE METHYL ESTER Eigenschaften

Siedepunkt:: 710.6±60.0 °C(Predicted)

Dichte: 1.224±0.06 g/cm3(Predicted)

Löslichkeit: Soluble in DMSO

pka: 13.22±0.46(Predicted)

Aggregatzustand: Solid

Sensitive: Light Sensitive & Hygroscopic

Sicherheit

4-[[N-(IMIDAZOL-4-YL)METHYLENEAMINO]-2-(1-NAPHTHYL)BENZOYL]LEUCINE METHYL ESTER Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

GGTI-2147 is an inhibitors of protein geranylgeranyltransferase-I and protein prenylation. Increases prelamin A accumulation by inhibiting ZMPSTE24 protein in human fibroblast and increases cytosolic accumulation of Rac1 and elicites significant inhibition of GSIS from INS 832/13 cells.

4-[[N-(IMIDAZOL-4-YL)METHYLENEAMINO]-2-(1-NAPHTHYL)BENZOYL]LEUCINE METHYL ESTER Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

4-[[N-(IMIDAZOL-4-YL)METHYLENEAMINO]-2-(1-NAPHTHYL)BENZOYL]LEUCINE METHYL ESTER Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 30)Lieferanten

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
Alpha Biopharmaceuticals Co., Ltd	+86-15542445688	sales@alabiochem.com	China	888	58
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	19892	58
Nextpeptide Inc	+86-0571-81612335 +8613336028439	sales@nextpeptide.com	China	19915	58
J & K SCIENTIFIC LTD.	010-82848833 400-666-7788	jkinfo@jkchemical.com	China	96815	76
Alabiochem Tech.Co., Ltd.	0512-58900862 400-0707518	sales@alabiochem.com	China	997	59
VDM Biochemicals	0330-2528181	sales@vdmbio.com	United States	510	64
Shanghai TaoSu Biochemical Technology Co., Ltd.	021-33632979	info@tsbiochem.com	China	8073	58
Alabiotech Inc.	001-619-354-5251	sales@alabiotech-e.com	United States	972	60
Alpha Biopharmaceuticals Co., Ltd	0411-39042497	sales@alphabiopharm.com	China	1951	58
Shenzhen Polymeri Biochemical Technology Co., Ltd.	+86-400-002-6226 13028896684	sales@rrkchem.com	China	56057	58

GGTI-2147
4-[[N-(IMIDAZOL-4-YL)METHYLENEAMINO]-2-(1-NAPHTHYL)BENZOYL]LEUCINE METHYL ESTER
TUQRZGWNDBXSNP-SANMLTNESA-N
GGTI-2147 (GGTI2147)
L-Leucine, N-[4-[(1H-imidazol-5-ylmethyl)amino]-2-(1-naphthalenyl)benzoyl]-, methyl ester
Geranylgeranyl transferase inhibitor-2147
191102-87-1
A cell-permeable non-thiol peptidomimetic that acts as a potent and selective inhibitor of geranylgeranyltransferase I (GGTase I).
Amino Acids & Derivatives, Chiral Reagents, Heterocycles, Inhibitors
Other enzyme inhibitors and activators